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Dysregulation in Akt/mTOR/HIF-1 signaling identified by proteo-transcriptomics of SARS-CoV-2 infected cells.
Appelberg S, Gupta S, Svensson Akusjärvi S, Ambikan AT, Mikaeloff F, Saccon E, Végvári Á, Benfeitas R, Sperk M, Ståhlberg M, Krishnan S, Singh K, Penninger JM, Mirazimi A, Neogi U. Appelberg S, et al. Among authors: benfeitas r. Emerg Microbes Infect. 2020 Dec;9(1):1748-1760. doi: 10.1080/22221751.2020.1799723. Emerg Microbes Infect. 2020. PMID: 32691695 Free PMC article.
Metabolic Perturbation Associated With COVID-19 Disease Severity and SARS-CoV-2 Replication.
Krishnan S, Nordqvist H, Ambikan AT, Gupta S, Sperk M, Svensson-Akusjärvi S, Mikaeloff F, Benfeitas R, Saccon E, Ponnan SM, Rodriguez JE, Nikouyan N, Odeh A, Ahlén G, Asghar M, Sällberg M, Vesterbacka J, Nowak P, Végvári Á, Sönnerborg A, Treutiger CJ, Neogi U. Krishnan S, et al. Among authors: benfeitas r. Mol Cell Proteomics. 2021;20:100159. doi: 10.1016/j.mcpro.2021.100159. Epub 2021 Oct 5. Mol Cell Proteomics. 2021. PMID: 34619366 Free PMC article.
The central role of the glutamate metabolism in long-term antiretroviral treated HIV-infected individuals with metabolic syndrome.
Gelpi M, Mikaeloff F, Knudsen AD, Benfeitas R, Krishnan S, Svenssson Akusjärvi S, Høgh J, Murray DD, Ullum H, Neogi U, Nielsen SD. Gelpi M, et al. Among authors: benfeitas r. Aging (Albany NY). 2021 Oct 11;13(19):22732-22751. doi: 10.18632/aging.203622. Epub 2021 Oct 11. Aging (Albany NY). 2021. PMID: 34635603 Free PMC article.
Trans cohort metabolic reprogramming towards glutaminolysis in long-term successfully treated HIV-infection.
Mikaeloff F, Svensson Akusjärvi S, Ikomey GM, Krishnan S, Sperk M, Gupta S, Magdaleno GDV, Escós A, Lyonga E, Okomo MC, Tagne CT, Babu H, Lorson CL, Végvári Á, Banerjea AC, Kele J, Hanna LE, Singh K, de Magalhães JP, Benfeitas R, Neogi U. Mikaeloff F, et al. Among authors: benfeitas r. Commun Biol. 2022 Jan 11;5(1):27. doi: 10.1038/s42003-021-02985-3. Commun Biol. 2022. PMID: 35017663 Free PMC article.
Multi-omics insights into host-viral response and pathogenesis in Crimean-Congo hemorrhagic fever viruses for novel therapeutic target.
Neogi U, Elaldi N, Appelberg S, Ambikan A, Kennedy E, Dowall S, Bagci BK, Gupta S, Rodriguez JE, Svensson-Akusjärvi S, Monteil V, Vegvari A, Benfeitas R, Banerjea A, Weber F, Hewson R, Mirazimi A. Neogi U, et al. Among authors: benfeitas r. Elife. 2022 Apr 19;11:e76071. doi: 10.7554/eLife.76071. Elife. 2022. PMID: 35437144 Free PMC article.
Multi-omics personalized network analyses highlight progressive disruption of central metabolism associated with COVID-19 severity.
Ambikan AT, Yang H, Krishnan S, Svensson Akusjärvi S, Gupta S, Lourda M, Sperk M, Arif M, Zhang C, Nordqvist H, Ponnan SM, Sönnerborg A, Treutiger CJ, O'Mahony L, Mardinoglu A, Benfeitas R, Neogi U. Ambikan AT, et al. Among authors: benfeitas r. Cell Syst. 2022 Aug 17;13(8):665-681.e4. doi: 10.1016/j.cels.2022.06.006. Epub 2022 Jul 8. Cell Syst. 2022. PMID: 35933992 Free PMC article.
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