Benaim G - Search Results

1

Amiodarone destabilizes intracellular Ca2+ homeostasis and biosynthesis of sterols in Leishmania mexicana.

Serrano-Martín X, García-Marchan Y, Fernandez A, Rodriguez N, Rojas H, Visbal G, Benaim G. Serrano-Martín X, et al. Among authors: benaim g. Antimicrob Agents Chemother. 2009 Apr;53(4):1403-10. doi: 10.1128/AAC.01215-08. Epub 2009 Jan 21. Antimicrob Agents Chemother. 2009. PMID: 19164149 Free PMC article.

We have recently shown that amiodarone, frequently used as an antiarrhythmic, possesses activity against Trypanosoma cruzi through the disruption of mitochondrial Ca(2+) homeostasis and the inhibition of parasite ergosterol biosynthesis, specifically at the level of oxidosqualene …

We have recently shown that amiodarone, frequently used as an antiarrhythmic, possesses activity against Trypanosoma cruzi through the disru …

2

Intracellular calcium homeostasis in Leishmania mexicana. Identification and characterization of a plasma membrane calmodulin-dependent Ca(2+)-ATPase.

Benaim G, Cervino V, Hermoso T, Felibert P, Laurentin A. Benaim G, et al. Biol Res. 1993;26(1-2):141-50. Biol Res. 1993. PMID: 7670527

3

Ouabain-sensitive Na+,K(+)-ATPase in the plasma membrane of Leishmania mexicana.

Felibertt P, Bermúdez R, Cervino V, Dawidowicz K, Dagger F, Proverbio T, Marín R, Benaim G. Felibertt P, et al. Among authors: benaim g. Mol Biochem Parasitol. 1995 Nov;74(2):179-87. doi: 10.1016/0166-6851(95)02497-2. Mol Biochem Parasitol. 1995. PMID: 8719159

4

Evaluation of the presence of a thapsigargin-sensitive calcium store in trypanosomatids using Trypanosoma evansi as a model.

Mendoza M, Mijares A, Rojas H, Colina C, Cervino V, DiPolo R, Benaim G. Mendoza M, et al. Among authors: benaim g. J Parasitol. 2004 Oct;90(5):1181-3. doi: 10.1645/GE-263R. J Parasitol. 2004. PMID: 15562626

5

Ceramide increase cytoplasmic Ca2+ concentration in Jurkat T cells by liberation of calcium from intracellular stores and activation of a store-operated calcium channel.

Colina C, Flores A, Rojas H, Acosta A, Castillo C, Garrido Mdel R, Israel A, DiPolo R, Benaim G. Colina C, et al. Among authors: benaim g. Arch Biochem Biophys. 2005 Apr 15;436(2):333-45. doi: 10.1016/j.abb.2005.02.014. Arch Biochem Biophys. 2005. PMID: 15797246

6

Amiodarone has intrinsic anti-Trypanosoma cruzi activity and acts synergistically with posaconazole.

Benaim G, Sanders JM, Garcia-Marchán Y, Colina C, Lira R, Caldera AR, Payares G, Sanoja C, Burgos JM, Leon-Rossell A, Concepcion JL, Schijman AG, Levin M, Oldfield E, Urbina JA. Benaim G, et al. J Med Chem. 2006 Feb 9;49(3):892-9. doi: 10.1021/jm050691f. J Med Chem. 2006. PMID: 16451055

7

Na+ entry via glutamate transporter activates the reverse Na+/Ca2+ exchange and triggers Ca(i)2+-induced Ca2+ release in rat cerebellar Type-1 astrocytes.

Rojas H, Colina C, Ramos M, Benaim G, Jaffe EH, Caputo C, DiPolo R. Rojas H, et al. Among authors: benaim g. J Neurochem. 2007 Mar;100(5):1188-202. doi: 10.1111/j.1471-4159.2006.04303.x. J Neurochem. 2007. PMID: 17316398 Free article.

8

The activity of the Na+/Ca2+ exchanger largely modulates the Ca2+i signal induced by hypo-osmotic stress in rat cerebellar astrocytes. The effect of osmolarity on exchange activity.

Rojas H, Ramos M, Benaim G, Caputo C, DiPolo R. Rojas H, et al. Among authors: benaim g. J Physiol Sci. 2008 Aug;58(4):277-9. doi: 10.2170/physiolsci.RP009208. Epub 2008 Jul 19. J Physiol Sci. 2008. PMID: 18638422 Free article.

9

Anti-VSG antibodies induce an increase in Trypanosoma evansi intracellular Ca2+ concentration.

Mendoza M, Uzcanga GL, Pacheco R, Rojas H, Carrasquel LM, García-Marchan Y, Serrano-Martín X, Benaím G, Bubis J, Mijares A. Mendoza M, et al. Among authors: benaim g. Parasitology. 2008 Sep;135(11):1303-15. doi: 10.1017/S0031182008004903. Epub 2008 Aug 28. Parasitology. 2008. PMID: 18752709

10

Trypanosoma cruzi calmodulin: cloning, expression and characterization.

Garcia-Marchan Y, Sojo F, Rodriguez E, Zerpa N, Malave C, Galindo-Castro I, Salerno M, Benaim G. Garcia-Marchan Y, et al. Among authors: benaim g. Exp Parasitol. 2009 Dec;123(4):326-33. doi: 10.1016/j.exppara.2009.08.010. Epub 2009 Aug 22. Exp Parasitol. 2009. PMID: 19703447

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