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102 results

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SARS-CoV-2 variants evolve convergent strategies to remodel the host response.
Bouhaddou M, Reuschl AK, Polacco BJ, Thorne LG, Ummadi MR, Ye C, Rosales R, Pelin A, Batra J, Jang GM, Xu J, Moen JM, Richards AL, Zhou Y, Harjai B, Stevenson E, Rojc A, Ragazzini R, Whelan MVX, Furnon W, De Lorenzo G, Cowton V, Syed AM, Ciling A, Deutsch N, Pirak D, Dowgier G, Mesner D, Turner JL, McGovern BL, Rodriguez ML, Leiva-Rebollo R, Dunham AS, Zhong X, Eckhardt M, Fossati A, Liotta NF, Kehrer T, Cupic A, Rutkowska M, Mena I, Aslam S, Hoffert A, Foussard H, Olwal CO, Huang W, Zwaka T, Pham J, Lyons M, Donohue L, Griffin A, Nugent R, Holden K, Deans R, Aviles P, Lopez-Martin JA, Jimeno JM, Obernier K, Fabius JM, Soucheray M, Hüttenhain R, Jungreis I, Kellis M, Echeverria I, Verba K, Bonfanti P, Beltrao P, Sharan R, Doudna JA, Martinez-Sobrido L, Patel AH, Palmarini M, Miorin L, White K, Swaney DL, Garcia-Sastre A, Jolly C, Zuliani-Alvarez L, Towers GJ, Krogan NJ. Bouhaddou M, et al. Among authors: beltrao p. Cell. 2023 Oct 12;186(21):4597-4614.e26. doi: 10.1016/j.cell.2023.08.026. Epub 2023 Sep 21. Cell. 2023. PMID: 37738970
High-throughput functional characterization of protein phosphorylation sites in yeast.
Viéitez C, Busby BP, Ochoa D, Mateus A, Memon D, Galardini M, Yildiz U, Trovato M, Jawed A, Geiger AG, Oborská-Oplová M, Potel CM, Vonesch SC, Szu Tu C, Shahraz M, Stein F, Steinmetz LM, Panse VG, Noh KM, Savitski MM, Typas A, Beltrao P. Viéitez C, et al. Among authors: beltrao p. Nat Biotechnol. 2022 Mar;40(3):382-390. doi: 10.1038/s41587-021-01051-x. Epub 2021 Oct 18. Nat Biotechnol. 2022. PMID: 34663920 Free PMC article.
Capturing variation impact on molecular interactions in the IMEx Consortium mutations data set.
IMEx Consortium Curators; Del-Toro N, Duesbury M, Koch M, Perfetto L, Shrivastava A, Ochoa D, Wagih O, Piñero J, Kotlyar M, Pastrello C, Beltrao P, Furlong LI, Jurisica I, Hermjakob H, Orchard S, Porras P. IMEx Consortium Curators, et al. Among authors: beltrao p. Nat Commun. 2019 Jan 2;10(1):10. doi: 10.1038/s41467-018-07709-6. Nat Commun. 2019. PMID: 30602777 Free PMC article.
Selective deployment of transcription factor paralogs with submaximal strength facilitates gene regulation in the immune system.
Bruno L, Ramlall V, Studer RA, Sauer S, Bradley D, Dharmalingam G, Carroll T, Ghoneim M, Chopin M, Nutt SL, Elderkin S, Rueda DS, Fisher AG, Siggers T, Beltrao P, Merkenschlager M. Bruno L, et al. Among authors: beltrao p. Nat Immunol. 2019 Oct;20(10):1372-1380. doi: 10.1038/s41590-019-0471-5. Epub 2019 Aug 26. Nat Immunol. 2019. PMID: 31451789 Free PMC article.
Evolvability and hierarchy in rewired bacterial gene networks.
Isalan M, Lemerle C, Michalodimitrakis K, Horn C, Beltrao P, Raineri E, Garriga-Canut M, Serrano L. Isalan M, et al. Among authors: beltrao p. Nature. 2008 Apr 17;452(7189):840-5. doi: 10.1038/nature06847. Nature. 2008. PMID: 18421347 Free PMC article.
Phenotype inference in an Escherichia coli strain panel.
Galardini M, Koumoutsi A, Herrera-Dominguez L, Cordero Varela JA, Telzerow A, Wagih O, Wartel M, Clermont O, Denamur E, Typas A, Beltrao P. Galardini M, et al. Among authors: beltrao p. Elife. 2017 Dec 27;6:e31035. doi: 10.7554/eLife.31035. Elife. 2017. PMID: 29280730 Free PMC article.
Causal integration of multi-omics data with prior knowledge to generate mechanistic hypotheses.
Dugourd A, Kuppe C, Sciacovelli M, Gjerga E, Gabor A, Emdal KB, Vieira V, Bekker-Jensen DB, Kranz J, Bindels EMJ, Costa ASH, Sousa A, Beltrao P, Rocha M, Olsen JV, Frezza C, Kramann R, Saez-Rodriguez J. Dugourd A, et al. Among authors: beltrao p. Mol Syst Biol. 2021 Jan;17(1):e9730. doi: 10.15252/msb.20209730. Mol Syst Biol. 2021. PMID: 33502086 Free PMC article.
102 results