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GPER deletion triggers inhibitory effects in triple negative breast cancer (TNBC) cells through the JNK/c-Jun/p53/Noxa transduction pathway.
Cirillo F, Talia M, Santolla MF, Pellegrino M, Scordamaglia D, Spinelli A, De Rosis S, Giordano F, Muglia L, Zicarelli A, Di Dio M, Rigiracciolo DC, Miglietta AM, Filippelli G, De Francesco EM, Belfiore A, Lappano R, Maggiolini M. Cirillo F, et al. Among authors: belfiore a. Cell Death Discov. 2023 Sep 26;9(1):353. doi: 10.1038/s41420-023-01654-0. Cell Death Discov. 2023. PMID: 37749101 Free PMC article.
The lauric acid-activated signaling prompts apoptosis in cancer cells.
Lappano R, Sebastiani A, Cirillo F, Rigiracciolo DC, Galli GR, Curcio R, Malaguarnera R, Belfiore A, Cappello AR, Maggiolini M. Lappano R, et al. Among authors: belfiore a. Cell Death Discov. 2017 Sep 18;3:17063. doi: 10.1038/cddiscovery.2017.63. eCollection 2017. Cell Death Discov. 2017. PMID: 28924490 Free PMC article.
Focal Adhesion Kinase (FAK)-Hippo/YAP transduction signaling mediates the stimulatory effects exerted by S100A8/A9-RAGE system in triple-negative breast cancer (TNBC).
Rigiracciolo DC, Nohata N, Lappano R, Cirillo F, Talia M, Adame-Garcia SR, Arang N, Lubrano S, De Francesco EM, Belfiore A, Gutkind JS, Maggiolini M. Rigiracciolo DC, et al. Among authors: belfiore a. J Exp Clin Cancer Res. 2022 Jun 3;41(1):193. doi: 10.1186/s13046-022-02396-0. J Exp Clin Cancer Res. 2022. PMID: 35655319 Free PMC article.
Metformin counteracts stimulatory effects induced by insulin in primary breast cancer cells.
Scordamaglia D, Cirillo F, Talia M, Santolla MF, Rigiracciolo DC, Muglia L, Zicarelli A, De Rosis S, Giordano F, Miglietta AM, De Francesco EM, Vella V, Belfiore A, Lappano R, Maggiolini M. Scordamaglia D, et al. Among authors: belfiore a. J Transl Med. 2022 Jun 7;20(1):263. doi: 10.1186/s12967-022-03463-y. J Transl Med. 2022. PMID: 35672854 Free PMC article.
Copper activates HIF-1α/GPER/VEGF signalling in cancer cells.
Rigiracciolo DC, Scarpelli A, Lappano R, Pisano A, Santolla MF, De Marco P, Cirillo F, Cappello AR, Dolce V, Belfiore A, Maggiolini M, De Francesco EM. Rigiracciolo DC, et al. Among authors: belfiore a. Oncotarget. 2015 Oct 27;6(33):34158-77. doi: 10.18632/oncotarget.5779. Oncotarget. 2015. PMID: 26415222 Free PMC article.
GPER, IGF-IR, and EGFR transduction signaling are involved in stimulatory effects of zinc in breast cancer cells and cancer-associated fibroblasts.
Pisano A, Santolla MF, De Francesco EM, De Marco P, Rigiracciolo DC, Perri MG, Vivacqua A, Abonante S, Cappello AR, Dolce V, Belfiore A, Maggiolini M, Lappano R. Pisano A, et al. Among authors: belfiore a. Mol Carcinog. 2017 Feb;56(2):580-593. doi: 10.1002/mc.22518. Epub 2016 Jul 4. Mol Carcinog. 2017. PMID: 27341075
338 results