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A new chemical tool (C0036E08) supports the role of adenosine A(2B) receptors in mediating human mast cell activation.
Buceta M, Domínguez E, Castro M, Brea J, Alvarez D, Barcala J, Valdés L, Alvarez-Calderón P, Domínguez F, Vidal B, Díaz JL, Miralpeix M, Beleta J, Cadavid MI, Loza MI. Buceta M, et al. Among authors: beleta j. Biochem Pharmacol. 2008 Oct 1;76(7):912-21. doi: 10.1016/j.bcp.2008.07.011. Epub 2008 Jul 19. Biochem Pharmacol. 2008. PMID: 18687311
Discovery and characterization of 4'-(2-furyl)-N-pyridin-3-yl-4,5'-bipyrimidin-2'-amine (LAS38096), a potent, selective, and efficacious A2B adenosine receptor antagonist.
Vidal B, Nueda A, Esteve C, Domenech T, Benito S, Reinoso RF, Pont M, Calbet M, López R, Cadavid MI, Loza MI, Cárdenas A, Godessart N, Beleta J, Warrellow G, Ryder H. Vidal B, et al. Among authors: beleta j. J Med Chem. 2007 May 31;50(11):2732-6. doi: 10.1021/jm061333v. Epub 2007 May 1. J Med Chem. 2007. PMID: 17469811
57 results