Belal A - Search Results

1

Metformin ameliorates doxorubicin-induced cardiotoxicity targeting HMGB1/TLR4/NLRP3 signaling pathway in mice.

Alzokaky AA, Al-Karmalawy AA, Saleh MA, Abdo W, Farage AE, Belal A, Abourehab MAS, Antar SA. Alzokaky AA, et al. Among authors: belal a. Life Sci. 2023 Mar 1;316:121390. doi: 10.1016/j.lfs.2023.121390. Epub 2023 Jan 14. Life Sci. 2023. PMID: 36649752

2

Design and Synthesis of New Quinoxaline Derivatives as Potential Histone Deacetylase Inhibitors Targeting Hepatocellular Carcinoma: In Silico, In Vitro, and SAR Studies.

Ma C, Taghour MS, Belal A, Mehany ABM, Mostafa N, Nabeeh A, Eissa IH, Al-Karmalawy AA. Ma C, et al. Among authors: belal a. Front Chem. 2021 Sep 22;9:725135. doi: 10.3389/fchem.2021.725135. eCollection 2021. Front Chem. 2021. PMID: 34631658 Free PMC article.

3

Screening a Panel of Topical Ophthalmic Medications against MMP-2 and MMP-9 to Investigate Their Potential in Keratoconus Management.

Belal A, Elanany MA, Santali EY, Al-Karmalawy AA, Aboelez MO, Amin AH, Abdellattif MH, Mehany ABM, Elkady H. Belal A, et al. Molecules. 2022 Jun 2;27(11):3584. doi: 10.3390/molecules27113584. Molecules. 2022. PMID: 35684529 Free PMC article.

4

Microwave-assisted synthesis, spectroscopic characterization, and biological evaluation of fused thieno[2,3-d]pyrimidines as potential anti-cancer agents targeting EGFR^WT and EGFR^T790M.

Aboelez MO, Kamel MS, Belal A, El Badry Abdel-Aziz A, Abourehab MAS, Abdel-Ghany H, A El Hamd M, El-Remaily MAEAA. Aboelez MO, et al. Among authors: a el hamd m, belal a. Mol Divers. 2023 Apr;27(2):901-917. doi: 10.1007/s11030-022-10477-7. Epub 2022 Jul 3. Mol Divers. 2023. PMID: 35780205

5

Design and synthesis of novel benzoazoninone derivatives as potential CBSIs and apoptotic inducers: In Vitro, in Vivo, molecular docking, molecular dynamics, and SAR studies.

Hammouda MM, Elmaaty AA, Nafie MS, Abdel-Motaal M, Mohamed NS, Tantawy MA, Belal A, Alnajjar R, Eldehna WM, Al-Karmalawy AA. Hammouda MM, et al. Among authors: belal a. Bioorg Chem. 2022 Oct;127:105995. doi: 10.1016/j.bioorg.2022.105995. Epub 2022 Jun 30. Bioorg Chem. 2022. PMID: 35792315

6

Design, synthesis and molecular docking of new fused 1H-pyrroles, pyrrolo[3,2-d]pyrimidines and pyrrolo[3,2-e][1, 4]diazepine derivatives as potent EGFR/CDK2 inhibitors.

Belal A, Abdel Gawad NM, Mehany ABM, Abourehab MAS, Elkady H, Al-Karmalawy AA, Ismael AS. Belal A, et al. J Enzyme Inhib Med Chem. 2022 Dec;37(1):1884-1902. doi: 10.1080/14756366.2022.2096019. J Enzyme Inhib Med Chem. 2022. PMID: 35801486 Free PMC article.

7

Discovery of Some Heterocyclic Molecules as Bone Morphogenetic Protein 2 (BMP-2)-Inducible Kinase Inhibitors: Virtual Screening, ADME Properties, and Molecular Docking Simulations.

Belal A, Elkady H, Al-Karmalawy AA, Amin AH, Ghoneim MM, El-Sherbiny M, Al-Serwi RH, Abdou MA, Ibrahim MH, Mehany ABM. Belal A, et al. Molecules. 2022 Aug 30;27(17):5571. doi: 10.3390/molecules27175571. Molecules. 2022. PMID: 36080338 Free PMC article.

8

Discovery of new symmetrical and asymmetrical nitrile-containing 1,4-dihydropyridine derivatives as dual kinases and P-glycoprotein inhibitors: synthesis, in vitro assays, and in silico studies.

Saad MH, El-Moselhy TF, S El-Din N, Mehany ABM, Belal A, Abourehab MAS, Tawfik HO, El-Hamamsy MH. Saad MH, et al. Among authors: belal a. J Enzyme Inhib Med Chem. 2022 Dec;37(1):2489-2511. doi: 10.1080/14756366.2022.2120478. J Enzyme Inhib Med Chem. 2022. PMID: 36093880 Free PMC article.

9

Dependence on linkers' flexibility designed for benzenesulfonamides targeting discovery of novel hCA IX inhibitors as potent anticancer agents.

Tawfik HO, Belal A, Abourehab MAS, Angeli A, Bonardi A, Supuran CT, El-Hamamsy MH. Tawfik HO, et al. Among authors: belal a. J Enzyme Inhib Med Chem. 2022 Dec;37(1):2765-2785. doi: 10.1080/14756366.2022.2130285. J Enzyme Inhib Med Chem. 2022. PMID: 36210545 Free PMC article.

10

Anticoagulants as Potential SARS-CoV-2 M^pro Inhibitors for COVID-19 Patients: In Vitro, Molecular Docking, Molecular Dynamics, DFT, and SAR Studies.

Abo Elmaaty A, Eldehna WM, Khattab M, Kutkat O, Alnajjar R, El-Taweel AN, Al-Rashood ST, Abourehab MAS, Binjubair FA, Saleh MA, Belal A, Al-Karmalawy AA. Abo Elmaaty A, et al. Among authors: belal a. Int J Mol Sci. 2022 Oct 13;23(20):12235. doi: 10.3390/ijms232012235. Int J Mol Sci. 2022. PMID: 36293094 Free PMC article.

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