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A small molecule G6PD inhibitor reveals immune dependence on pentose phosphate pathway.
Ghergurovich JM, García-Cañaveras JC, Wang J, Schmidt E, Zhang Z, TeSlaa T, Patel H, Chen L, Britt EC, Piqueras-Nebot M, Gomez-Cabrera MC, Lahoz A, Fan J, Beier UH, Kim H, Rabinowitz JD. Ghergurovich JM, et al. Among authors: beier uh. Nat Chem Biol. 2020 Jul;16(7):731-739. doi: 10.1038/s41589-020-0533-x. Epub 2020 May 11. Nat Chem Biol. 2020. PMID: 32393898 Free PMC article.
Lactate Limits T Cell Proliferation via the NAD(H) Redox State.
Quinn WJ 3rd, Jiao J, TeSlaa T, Stadanlick J, Wang Z, Wang L, Akimova T, Angelin A, Schäfer PM, Cully MD, Perry C, Kopinski PK, Guo L, Blair IA, Ghanem LR, Leibowitz MS, Hancock WW, Moon EK, Levine MH, Eruslanov EB, Wallace DC, Baur JA, Beier UH. Quinn WJ 3rd, et al. Among authors: beier uh. Cell Rep. 2020 Dec 15;33(11):108500. doi: 10.1016/j.celrep.2020.108500. Cell Rep. 2020. PMID: 33326785 Free PMC article.
Histone/protein deacetylases and T-cell immune responses.
Akimova T, Beier UH, Liu Y, Wang L, Hancock WW. Akimova T, et al. Among authors: beier uh. Blood. 2012 Mar 15;119(11):2443-51. doi: 10.1182/blood-2011-10-292003. Epub 2012 Jan 12. Blood. 2012. PMID: 22246031 Free PMC article. Review.
HDAC inhibitor therapy in autoimmunity and transplantation.
Hancock WW, Akimova T, Beier UH, Liu Y, Wang L. Hancock WW, et al. Among authors: beier uh. Ann Rheum Dis. 2012 Apr;71 Suppl 2:i46-54. doi: 10.1136/annrheumdis-2011-200593. Ann Rheum Dis. 2012. PMID: 22460138 Review.
Sirtuin-1 in immunotherapy: A Janus-headed target.
Chadha S, Wang L, Hancock WW, Beier UH. Chadha S, et al. Among authors: beier uh. J Leukoc Biol. 2019 Aug;106(2):337-343. doi: 10.1002/JLB.2RU1118-422R. Epub 2019 Jan 3. J Leukoc Biol. 2019. PMID: 30605226 Free PMC article. Review.
74 results