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Distinct Classes of Complex Structural Variation Uncovered across Thousands of Cancer Genome Graphs.
Hadi K, Yao X, Behr JM, Deshpande A, Xanthopoulakis C, Tian H, Kudman S, Rosiene J, Darmofal M, DeRose J, Mortensen R, Adney EM, Shaiber A, Gajic Z, Sigouros M, Eng K, Wala JA, Wrzeszczyński KO, Arora K, Shah M, Emde AK, Felice V, Frank MO, Darnell RB, Ghandi M, Huang F, Dewhurst S, Maciejowski J, de Lange T, Setton J, Riaz N, Reis-Filho JS, Powell S, Knowles DA, Reznik E, Mishra B, Beroukhim R, Zody MC, Robine N, Oman KM, Sanchez CA, Kuhner MK, Smith LP, Galipeau PC, Paulson TG, Reid BJ, Li X, Wilkes D, Sboner A, Mosquera JM, Elemento O, Imielinski M. Hadi K, et al. Among authors: behr jm. Cell. 2020 Oct 1;183(1):197-210.e32. doi: 10.1016/j.cell.2020.08.006. Cell. 2020. PMID: 33007263 Free PMC article.
Structural variant evolution after telomere crisis.
Dewhurst SM, Yao X, Rosiene J, Tian H, Behr J, Bosco N, Takai KK, de Lange T, Imieliński M. Dewhurst SM, et al. Nat Commun. 2021 Apr 7;12(1):2093. doi: 10.1038/s41467-021-21933-7. Nat Commun. 2021. PMID: 33828097 Free PMC article.
Identifying synergistic high-order 3D chromatin conformations from genome-scale nanopore concatemer sequencing.
Deshpande AS, Ulahannan N, Pendleton M, Dai X, Ly L, Behr JM, Schwenk S, Liao W, Augello MA, Tyer C, Rughani P, Kudman S, Tian H, Otis HG, Adney E, Wilkes D, Mosquera JM, Barbieri CE, Melnick A, Stoddart D, Turner DJ, Juul S, Harrington E, Imieliński M. Deshpande AS, et al. Among authors: behr jm. Nat Biotechnol. 2022 Oct;40(10):1488-1499. doi: 10.1038/s41587-022-01289-z. Epub 2022 May 30. Nat Biotechnol. 2022. PMID: 35637420
Long-molecule scars of backup DNA repair in BRCA1- and BRCA2-deficient cancers.
Setton J, Hadi K, Choo ZN, Kuchin KS, Tian H, Da Cruz Paula A, Rosiene J, Selenica P, Behr J, Yao X, Deshpande A, Sigouros M, Manohar J, Nauseef JT, Mosquera JM, Elemento O, Weigelt B, Riaz N, Reis-Filho JS, Powell SN, Imieliński M. Setton J, et al. Among authors: behr j. Nature. 2023 Sep;621(7977):129-137. doi: 10.1038/s41586-023-06461-2. Epub 2023 Aug 16. Nature. 2023. PMID: 37587346 Free PMC article.
Most large structural variants in cancer genomes can be detected without long reads.
Choo ZN, Behr JM, Deshpande A, Hadi K, Yao X, Tian H, Takai K, Zakusilo G, Rosiene J, Da Cruz Paula A, Weigelt B, Setton J, Riaz N, Powell SN, Busam K, Shoushtari AN, Ariyan C, Reis-Filho J, de Lange T, Imieliński M. Choo ZN, et al. Among authors: behr jm. Nat Genet. 2023 Dec;55(12):2139-2148. doi: 10.1038/s41588-023-01540-6. Epub 2023 Nov 9. Nat Genet. 2023. PMID: 37945902 Free PMC article.
An Open Library of Human Kinase Domain Constructs for Automated Bacterial Expression.
Albanese SK, Parton DL, Işık M, Rodríguez-Laureano L, Hanson SM, Behr JM, Gradia S, Jeans C, Levinson NM, Seeliger MA, Chodera JD. Albanese SK, et al. Among authors: behr jm. Biochemistry. 2018 Aug 7;57(31):4675-4689. doi: 10.1021/acs.biochem.7b01081. Epub 2018 Jul 26. Biochemistry. 2018. PMID: 30004690 Free PMC article.
13 results