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Page 1
Orai1 Channel Inhibition Preserves Left Ventricular Systolic Function and Normal Ca2+ Handling After Pressure Overload.
Bartoli F, Bailey MA, Rode B, Mateo P, Antigny F, Bedouet K, Gerbaud P, Gosain R, Plante J, Norman K, Gomez S, Lefebvre F, Rucker-Martin C, Ainscough JFX, Kearney MT, Bruns AF, Shi J, Appleby HL, Young RS, Shawer HM, Debant M, Gomez AM, Beech DJ, Foster R, Benitah JP, Sabourin J. Bartoli F, et al. Among authors: beech dj. Circulation. 2020 Jan 21;141(3):199-216. doi: 10.1161/CIRCULATIONAHA.118.038891. Epub 2020 Jan 7. Circulation. 2020. PMID: 31906693 Free PMC article.
Upregulated TRPC1 channel in vascular injury in vivo and its role in human neointimal hyperplasia.
Kumar B, Dreja K, Shah SS, Cheong A, Xu SZ, Sukumar P, Naylor J, Forte A, Cipollaro M, McHugh D, Kingston PA, Heagerty AM, Munsch CM, Bergdahl A, Hultgårdh-Nilsson A, Gomez MF, Porter KE, Hellstrand P, Beech DJ. Kumar B, et al. Among authors: beech dj. Circ Res. 2006 Mar 3;98(4):557-63. doi: 10.1161/01.RES.0000204724.29685.db. Epub 2006 Jan 26. Circ Res. 2006. PMID: 16439693 Free PMC article.
Pregnenolone sulphate- and cholesterol-regulated TRPM3 channels coupled to vascular smooth muscle secretion and contraction.
Naylor J, Li J, Milligan CJ, Zeng F, Sukumar P, Hou B, Sedo A, Yuldasheva N, Majeed Y, Beri D, Jiang S, Seymour VA, McKeown L, Kumar B, Harteneck C, O'Regan D, Wheatcroft SB, Kearney MT, Jones C, Porter KE, Beech DJ. Naylor J, et al. Among authors: beech dj. Circ Res. 2010 May 14;106(9):1507-15. doi: 10.1161/CIRCRESAHA.110.219329. Epub 2010 Apr 1. Circ Res. 2010. PMID: 20360246 Free PMC article.
The insulin-like growth factor-1 receptor is a negative regulator of nitric oxide bioavailability and insulin sensitivity in the endothelium.
Abbas A, Imrie H, Viswambharan H, Sukumar P, Rajwani A, Cubbon RM, Gage M, Smith J, Galloway S, Yuldeshava N, Kahn M, Xuan S, Grant PJ, Channon KM, Beech DJ, Wheatcroft SB, Kearney MT. Abbas A, et al. Among authors: beech dj. Diabetes. 2011 Aug;60(8):2169-78. doi: 10.2337/db11-0197. Epub 2011 Jun 15. Diabetes. 2011. PMID: 21677284 Free PMC article.
Platelet-derived growth factor maintains stored calcium through a nonclustering Orai1 mechanism but evokes clustering if the endoplasmic reticulum is stressed by store depletion.
McKeown L, Moss NK, Turner P, Li J, Heath N, Burke D, O'Regan D, Gilthorpe MS, Porter KE, Beech DJ. McKeown L, et al. Among authors: beech dj. Circ Res. 2012 Jun 22;111(1):66-76. doi: 10.1161/CIRCRESAHA.111.263616. Epub 2012 May 3. Circ Res. 2012. PMID: 22556336 Free PMC article.
Novel role of the IGF-1 receptor in endothelial function and repair: studies in endothelium-targeted IGF-1 receptor transgenic mice.
Imrie H, Viswambharan H, Sukumar P, Abbas A, Cubbon RM, Yuldasheva N, Gage M, Smith J, Galloway S, Skromna A, Rashid ST, Futers TS, Xuan S, Gatenby VK, Grant PJ, Channon KM, Beech DJ, Wheatcroft SB, Kearney MT. Imrie H, et al. Among authors: beech dj. Diabetes. 2012 Sep;61(9):2359-68. doi: 10.2337/db11-1494. Epub 2012 Jun 25. Diabetes. 2012. PMID: 22733797 Free PMC article.
256 results