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Mithramycin induces promoter reprogramming and differentiation of rhabdoid tumor.
Chasse MH, Johnson BK, Boguslawski EA, Sorensen KM, Rosien JE, Kang MH, Reynolds CP, Heo L, Madaj ZB, Beddows I, Foxa GE, Kitchen-Goosen SM, Williams BO, Triche TJ Jr, Grohar PJ. Chasse MH, et al. Among authors: beddows i. EMBO Mol Med. 2021 Feb 5;13(2):e12640. doi: 10.15252/emmm.202012640. Epub 2020 Dec 17. EMBO Mol Med. 2021. PMID: 33332735 Free PMC article.
CDK9 Blockade Exploits Context-dependent Transcriptional Changes to Improve Activity and Limit Toxicity of Mithramycin for Ewing Sarcoma.
Flores G, Everett JH, Boguslawski EA, Oswald BM, Madaj ZB, Beddows I, Dikalov S, Adams M, Klumpp-Thomas CA, Kitchen-Goosen SM, Martin SE, Caplen NJ, Helman LJ, Grohar PJ. Flores G, et al. Among authors: beddows i. Mol Cancer Ther. 2020 May;19(5):1183-1196. doi: 10.1158/1535-7163.MCT-19-0775. Epub 2020 Mar 3. Mol Cancer Ther. 2020. PMID: 32127464 Free PMC article.
Rare cases of medulloblastoma with hypermutation.
Bagchi A, Beddows I, Cornelius A, Robinson GW, Jewell SD. Bagchi A, et al. Among authors: beddows i. Cancer Rep (Hoboken). 2022 May;5(5):e1521. doi: 10.1002/cnr2.1521. Epub 2021 Aug 5. Cancer Rep (Hoboken). 2022. PMID: 34351088 Free PMC article.
Detection of Chemotherapy-resistant Pancreatic Cancer Using a Glycan Biomarker, sTRA.
Gao C, Wisniewski L, Liu Y, Staal B, Beddows I, Plenker D, Aldakkak M, Hall J, Barnett D, Gouda MK, Allen P, Drake R, Zureikat A, Huang Y, Evans D, Singhi A, Brand RE, Tuveson DA, Tsai S, Haab BB. Gao C, et al. Among authors: beddows i. Clin Cancer Res. 2021 Jan 1;27(1):226-236. doi: 10.1158/1078-0432.CCR-20-2475. Epub 2020 Oct 22. Clin Cancer Res. 2021. PMID: 33093149 Free PMC article.
19 results