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NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22.
Spalinger MR, Kasper S, Gottier C, Lang S, Atrott K, Vavricka SR, Scharl S, Raselli T, Frey-Wagner I, Gutte PM, Grütter MG, Beer HD, Contassot E, Chan AC, Dai X, Rawlings DJ, Mair F, Becher B, Falk W, Fried M, Rogler G, Scharl M. Spalinger MR, et al. Among authors: becher b. J Clin Invest. 2016 May 2;126(5):1783-800. doi: 10.1172/JCI83669. Epub 2016 Apr 4. J Clin Invest. 2016. PMID: 27043286 Free PMC article.
Epithelial IL-23R Signaling Licenses Protective IL-22 Responses in Intestinal Inflammation.
Aden K, Rehman A, Falk-Paulsen M, Secher T, Kuiper J, Tran F, Pfeuffer S, Sheibani-Tezerji R, Breuer A, Luzius A, Jentzsch M, Häsler R, Billmann-Born S, Will O, Lipinski S, Bharti R, Adolph T, Iovanna JL, Kempster SL, Blumberg RS, Schreiber S, Becher B, Chamaillard M, Kaser A, Rosenstiel P. Aden K, et al. Among authors: becher b. Cell Rep. 2016 Aug 23;16(8):2208-2218. doi: 10.1016/j.celrep.2016.07.054. Epub 2016 Aug 11. Cell Rep. 2016. PMID: 27524624 Free PMC article.
NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22.
Spalinger MR, Kasper S, Gottier C, Lang S, Atrott K, Vavricka SR, Scharl S, Raselli T, Frey-Wagner I, Gutte PM, Grütter MG, Beer HD, Contassot E, Chan AC, Dai X, Rawlings DJ, Mair F, Becher B, Falk W, Fried M, Rogler G, Scharl M. Spalinger MR, et al. Among authors: becher b. J Clin Invest. 2016 Nov 1;126(11):4388. doi: 10.1172/JCI90897. Epub 2016 Nov 1. J Clin Invest. 2016. PMID: 27801679 Free PMC article. No abstract available.
Protein Tyrosine Phosphatase Non-Receptor Type 2 Function in Dendritic Cells Is Crucial to Maintain Tissue Tolerance.
Hering L, Katkeviciute E, Schwarzfischer M, Busenhart P, Gottier C, Mrdjen D, Komuczki J, Wawrzyniak M, Lang S, Atrott K, Becher B, Rogler G, Scharl M, Spalinger MR. Hering L, et al. Among authors: becher b. Front Immunol. 2020 Aug 18;11:1856. doi: 10.3389/fimmu.2020.01856. eCollection 2020. Front Immunol. 2020. PMID: 32973765 Free PMC article.
Group 3 Innate Lymphoid Cells Program a Distinct Subset of IL-22BP-Producing Dendritic Cells Demarcating Solitary Intestinal Lymphoid Tissues.
Guendel F, Kofoed-Branzk M, Gronke K, Tizian C, Witkowski M, Cheng HW, Heinz GA, Heinrich F, Durek P, Norris PS, Ware CF, Ruedl C, Herold S, Pfeffer K, Hehlgans T, Waisman A, Becher B, Giannou AD, Brachs S, Ebert K, Tanriver Y, Ludewig B, Mashreghi MF, Kruglov AA, Diefenbach A. Guendel F, et al. Among authors: becher b. Immunity. 2020 Nov 17;53(5):1015-1032.e8. doi: 10.1016/j.immuni.2020.10.012. Immunity. 2020. PMID: 33207209 Free article.
Protection against autoimmunity is driven by thymic epithelial cell-mediated regulation of Treg development.
Haftmann C, Zwicky P, Ingelfinger F, Mair F, Floess S, Riedel R, Durek P, Spalinger MR, Friebel E, Leung BP, Lutz M, Puertas N, Amorim A, Schärli S, Becher B, Kisielow J, Waisman A, Mashreghi MF, Huehn J, Becher B. Haftmann C, et al. Among authors: becher b. Sci Immunol. 2021 Nov 19;6(65):eabf3111. doi: 10.1126/sciimmunol.abf3111. Epub 2021 Nov 19. Sci Immunol. 2021. PMID: 34797691
303 results