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Endothelial OCT4 is atheroprotective by preventing metabolic and phenotypic dysfunction.
Shin J, Tkachenko S, Chaklader M, Pletz C, Singh K, Bulut GB, Han YM, Mitchell K, Baylis RA, Kuzmin AA, Hu B, Lathia JD, Stenina-Adognravi O, Podrez E, Byzova TV, Owens GK, Cherepanova OA. Shin J, et al. Among authors: baylis ra. Cardiovasc Res. 2022 Aug 24;118(11):2458-2477. doi: 10.1093/cvr/cvac036. Cardiovasc Res. 2022. PMID: 35325071 Free PMC article.
Interleukin-1β has atheroprotective effects in advanced atherosclerotic lesions of mice.
Gomez D, Baylis RA, Durgin BG, Newman AAC, Alencar GF, Mahan S, St Hilaire C, Müller W, Waisman A, Francis SE, Pinteaux E, Randolph GJ, Gram H, Owens GK. Gomez D, et al. Among authors: baylis ra. Nat Med. 2018 Sep;24(9):1418-1429. doi: 10.1038/s41591-018-0124-5. Epub 2018 Jul 23. Nat Med. 2018. PMID: 30038218 Free PMC article.
Stem Cell Pluripotency Genes Klf4 and Oct4 Regulate Complex SMC Phenotypic Changes Critical in Late-Stage Atherosclerotic Lesion Pathogenesis.
Alencar GF, Owsiany KM, Karnewar S, Sukhavasi K, Mocci G, Nguyen AT, Williams CM, Shamsuzzaman S, Mokry M, Henderson CA, Haskins R, Baylis RA, Finn AV, McNamara CA, Zunder ER, Venkata V, Pasterkamp G, Björkegren J, Bekiranov S, Owens GK. Alencar GF, et al. Among authors: baylis ra. Circulation. 2020 Nov 24;142(21):2045-2059. doi: 10.1161/CIRCULATIONAHA.120.046672. Epub 2020 Jul 17. Circulation. 2020. PMID: 32674599 Free PMC article.
Multiple cell types contribute to the atherosclerotic lesion fibrous cap by PDGFRβ and bioenergetic mechanisms.
Newman AAC, Serbulea V, Baylis RA, Shankman LS, Bradley X, Alencar GF, Owsiany K, Deaton RA, Karnewar S, Shamsuzzaman S, Salamon A, Reddy MS, Guo L, Finn A, Virmani R, Cherepanova OA, Owens GK. Newman AAC, et al. Among authors: baylis ra. Nat Metab. 2021 Feb;3(2):166-181. doi: 10.1038/s42255-020-00338-8. Epub 2021 Feb 22. Nat Metab. 2021. PMID: 33619382 Free PMC article.
IL-1β inhibition partially negates the beneficial effects of diet-induced lipid lowering.
Karnewar S, Karnewar V, Deaton R, Shankman LS, Benavente ED, Williams CM, Bradley X, Alencar GF, Bulut GB, Kirmani S, Baylis RA, Zunder ER, den Ruijter HM, Pasterkamp G, Owens GK. Karnewar S, et al. Among authors: baylis ra. bioRxiv [Preprint]. 2023 Oct 14:2023.10.13.562255. doi: 10.1101/2023.10.13.562255. bioRxiv. 2023. PMID: 37873280 Free PMC article. Updated. Preprint.
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