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Discovery of potent and selective HER2 inhibitors with efficacy against HER2 exon 20 insertion-driven tumors, which preserve wild-type EGFR signaling.
Wilding B, Scharn D, Böse D, Baum A, Santoro V, Chetta P, Schnitzer R, Botesteanu DA, Reiser C, Kornigg S, Knesl P, Hörmann A, Köferle A, Corcokovic M, Lieb S, Scholz G, Bruchhaus J, Spina M, Balla J, Peric-Simov B, Zimmer J, Mitzner S, Fett TN, Beran A, Lamarre L, Gerstberger T, Gerlach D, Bauer M, Bergner A, Schlattl A, Bader G, Treu M, Engelhardt H, Zahn S, Fuchs JE, Zuber J, Ettmayer P, Pearson M, Petronczki M, Kraut N, McConnell DB, Solca F, Neumüller RA. Wilding B, et al. Among authors: bauer m. Nat Cancer. 2022 Jul;3(7):821-836. doi: 10.1038/s43018-022-00412-y. Epub 2022 Jul 26. Nat Cancer. 2022. PMID: 35883003
Discovery of Novel Spiro[3H-indole-3,2'-pyrrolidin]-2(1H)-one Compounds as Chemically Stable and Orally Active Inhibitors of the MDM2-p53 Interaction.
Gollner A, Rudolph D, Arnhof H, Bauer M, Blake SM, Boehmelt G, Cockroft XL, Dahmann G, Ettmayer P, Gerstberger T, Karolyi-Oezguer J, Kessler D, Kofink C, Ramharter J, Rinnenthal J, Savchenko A, Schnitzer R, Weinstabl H, Weyer-Czernilofsky U, Wunberg T, McConnell DB. Gollner A, et al. Among authors: bauer m. J Med Chem. 2016 Nov 23;59(22):10147-10162. doi: 10.1021/acs.jmedchem.6b00900. Epub 2016 Nov 15. J Med Chem. 2016. PMID: 27775892
Hormesis as an adaptive response to infection.
Bauer M, Ermolaeva M, Singer M, Wetzker R, Soares MP. Bauer M, et al. Trends Mol Med. 2024 May 13:S1471-4914(24)00100-X. doi: 10.1016/j.molmed.2024.04.012. Online ahead of print. Trends Mol Med. 2024. PMID: 38744580 Review.
The DESTINY+ Dust Analyser - a dust telescope for analysing cosmic dust dynamics and composition.
Simolka J, Blanco R, Ingerl S, Krüger H, Sommer M, Srama R, Strack H, Wagner C, Arai T, Bauer M, Fröhlich P, Gläser J, Gräßlin M, Henselowsky C, Hillier J, Hirai T, Ito M, Kempf S, Khawaja N, Kimura H, Klinkner S, Kobayashi M, Lengowski M, Li Y, Mocker A, Moragas-Klostermeyer G, Postberg F, Rieth F, Sasaki S, Schmidt J, Sterken V, Sternovsky Z, Strub P, Szalay J, Trieloff M, Yabuta H. Simolka J, et al. Among authors: bauer m. Philos Trans A Math Phys Eng Sci. 2024 Jun 9;382(2273):20230199. doi: 10.1098/rsta.2023.0199. Epub 2024 May 13. Philos Trans A Math Phys Eng Sci. 2024. PMID: 38736332
Medical comorbidities in bipolar disorder (BIPCOM): clinical validation of risk factors and biomarkers to improve prevention and treatment. Study protocol.
de Girolamo G, Andreassen OA, Bauer M, Brambilla P, Calza S, Citerà N, Corcoy R, Fagiolini A, Garcia-Argibay M, Godin O, Klingler F, Kobayashi NF, Larsson H, Leboyer M, Matura S, Martinelli A, De la Peña-Arteaga V, Poli R, Reif A, Ritter P, Rødevand LN, Magno M, Caselani E; BIPCOM consortium. de Girolamo G, et al. Among authors: bauer m. Int J Bipolar Disord. 2024 May 4;12(1):15. doi: 10.1186/s40345-024-00337-8. Int J Bipolar Disord. 2024. PMID: 38703295 Free PMC article.
4,219 results