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Human distal airways contain a multipotent secretory cell that can regenerate alveoli.
Basil MC, Cardenas-Diaz FL, Kathiriya JJ, Morley MP, Carl J, Brumwell AN, Katzen J, Slovik KJ, Babu A, Zhou S, Kremp MM, McCauley KB, Li S, Planer JD, Hussain SS, Liu X, Windmueller R, Ying Y, Stewart KM, Oyster M, Christie JD, Diamond JM, Engelhardt JF, Cantu E, Rowe SM, Kotton DN, Chapman HA, Morrisey EE. Basil MC, et al. Nature. 2022 Apr;604(7904):120-126. doi: 10.1038/s41586-022-04552-0. Epub 2022 Mar 30. Nature. 2022. PMID: 35355013 Free PMC article.
An SFTPC BRICHOS mutant links epithelial ER stress and spontaneous lung fibrosis.
Katzen J, Wagner BD, Venosa A, Kopp M, Tomer Y, Russo SJ, Headen AC, Basil MC, Stark JM, Mulugeta S, Deterding RR, Beers MF. Katzen J, et al. Among authors: basil mc. JCI Insight. 2019 Mar 21;4(6):e126125. doi: 10.1172/jci.insight.126125. eCollection 2019 Mar 21. JCI Insight. 2019. PMID: 30721158 Free PMC article.
Lung regeneration: a tale of mice and men.
Basil MC, Morrisey EE. Basil MC, et al. Semin Cell Dev Biol. 2020 Apr;100:88-100. doi: 10.1016/j.semcdb.2019.11.006. Epub 2019 Nov 21. Semin Cell Dev Biol. 2020. PMID: 31761445 Free PMC article. Review.
STAT3-BDNF-TrkB signalling promotes alveolar epithelial regeneration after lung injury.
Paris AJ, Hayer KE, Oved JH, Avgousti DC, Toulmin SA, Zepp JA, Zacharias WJ, Katzen JB, Basil MC, Kremp MM, Slamowitz AR, Jayachandran S, Sivakumar A, Dai N, Wang P, Frank DB, Eisenlohr LC, Cantu E 3rd, Beers MF, Weitzman MD, Morrisey EE, Worthen GS. Paris AJ, et al. Among authors: basil mc. Nat Cell Biol. 2020 Oct;22(10):1197-1210. doi: 10.1038/s41556-020-0569-x. Epub 2020 Sep 28. Nat Cell Biol. 2020. PMID: 32989251 Free PMC article.
mTORC1 activation in lung mesenchyme drives sex- and age-dependent pulmonary structure and function decline.
Obraztsova K, Basil MC, Rue R, Sivakumar A, Lin SM, Mukhitov AR, Gritsiuta AI, Evans JF, Kopp M, Katzen J, Robichaud A, Atochina-Vasserman EN, Li S, Carl J, Babu A, Morley MP, Cantu E, Beers MF, Frank DB, Morrisey EE, Krymskaya VP. Obraztsova K, et al. Among authors: basil mc. Nat Commun. 2020 Nov 6;11(1):5640. doi: 10.1038/s41467-020-18979-4. Nat Commun. 2020. PMID: 33159078 Free PMC article.
Genomic, epigenomic, and biophysical cues controlling the emergence of the lung alveolus.
Zepp JA, Morley MP, Loebel C, Kremp MM, Chaudhry FN, Basil MC, Leach JP, Liberti DC, Niethamer TK, Ying Y, Jayachandran S, Babu A, Zhou S, Frank DB, Burdick JA, Morrisey EE. Zepp JA, et al. Among authors: basil mc. Science. 2021 Mar 12;371(6534):eabc3172. doi: 10.1126/science.abc3172. Science. 2021. PMID: 33707239 Free PMC article.
33 results