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Developmental trajectories and cooperating genomic events define molecular subtypes of BCR::ABL1-positive ALL.
Blood. 2024 Apr 4;143(14):1391-1398. doi: 10.1182/blood.2023021752.
Blood. 2024.
PMID: 38153913
Free PMC article.
The Gene Expression Classifier ALLCatchR Identifies B-cell Precursor ALL Subtypes and Underlying Developmental Trajectories Across Age.
Beder T, Hansen BT, Hartmann AM, Zimmermann J, Amelunxen E, Wolgast N, Walter W, Zaliova M, Antić Ž, Chouvarine P, Bartsch L, Barz MJ, Bultmann M, Horns J, Bendig S, Kässens J, Kaleta C, Cario G, Schrappe M, Neumann M, Gökbuget N, Bergmann AK, Trka J, Haferlach C, Brüggemann M, Baldus CD, Bastian L.
Beder T, et al. Among authors: barz mj.
Hemasphere. 2023 Aug 25;7(9):e939. doi: 10.1097/HS9.0000000000000939. eCollection 2023 Sep.
Hemasphere. 2023.
PMID: 37645423
Free PMC article.
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The hematopoietic stem cell marker VNN2 is associated with chemoresistance in pediatric B-cell precursor ALL.
Bornhauser B, Cario G, Rinaldi A, Risch T, Rodriguez Martinez V, Schütte M, Warnatz HJ, Scheidegger N, Mirkowska P, Temperli M, Möller C, Schumich A, Dworzak M, Attarbaschi A, Brüggemann M, Ritgen M, Mejstrikova E, Hofmann A, Buldini B, Scarparo P, Basso G, Maglia O, Gaipa G, Skoblyn TL, Te Kronnie G, Vendramini E, Panzer-Grümayer R, Barz MJ, Marovca B, Hauri-Hohl M, Niggli F, Eckert C, Schrappe M, Stanulla M, Zimmermann M, Wollscheid B, Yaspo ML, Bourquin JP.
Bornhauser B, et al. Among authors: barz mj.
Blood Adv. 2020 Sep 8;4(17):4052-4064. doi: 10.1182/bloodadvances.2019000938.
Blood Adv. 2020.
PMID: 32853382
Free PMC article.
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Subclonal NT5C2 mutations are associated with poor outcomes after relapse of pediatric acute lymphoblastic leukemia.
Barz MJ, Hof J, Groeneveld-Krentz S, Loh JW, Szymansky A, Astrahantseff K, von Stackelberg A, Khiabanian H, Ferrando AA, Eckert C, Kirschner-Schwabe R.
Barz MJ, et al.
Blood. 2020 Mar 19;135(12):921-933. doi: 10.1182/blood.2019002499.
Blood. 2020.
PMID: 31971569
Free PMC article.
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X-linked inhibitor of apoptosis protein represents a promising therapeutic target for relapsed/refractory ALL.
Carlet M, Schmelz K, Vergalli J, Herold T, Senft D, Jurinovic V, Hoffmann T, Proba J, Weichert N, Junghanß C, Roth M, Eschenburg G, Barz M, Henze G, Eckert C, Eggert A, Zuber J, Hundsdoerfer P, Jeremias I.
Carlet M, et al.
EMBO Mol Med. 2023 Jan 11;15(1):e14557. doi: 10.15252/emmm.202114557. Epub 2022 Nov 23.
EMBO Mol Med. 2023.
PMID: 36416169
Free PMC article.
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B- and T-cell acute lymphoblastic leukemias evade chemotherapy at distinct sites in the bone marrow.
Barz MJ, Behrmann L, Capron D, Zuchtriegel G, Steffen FD, Kunz L, Zhang Y, Vermeerbergen IJ, Marovca B, Kirschmann M, Zech A, Nombela-Arrieta C, Ziegler U, Schroeder T, Bornhauser B, Bourquin JP.
Barz MJ, et al.
Haematologica. 2023 May 1;108(5):1244-1258. doi: 10.3324/haematol.2021.280451.
Haematologica. 2023.
PMID: 36325888
Free PMC article.
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Chemotherapy and mismatch repair deficiency cooperate to fuel TP53 mutagenesis and ALL relapse.
Yang F, Brady SW, Tang C, Sun H, Du L, Barz MJ, Ma X, Chen Y, Fang H, Li X, Kolekar P, Pathak O, Cai J, Ding L, Wang T, von Stackelberg A, Shen S, Eckert C, Klco JM, Chen H, Duan C, Liu Y, Li H, Li B, Kirschner-Schwabe R, Zhang J, Zhou BS.
Yang F, et al. Among authors: barz mj.
Nat Cancer. 2021 Aug;2(8):819-834. doi: 10.1038/s43018-021-00230-8. Epub 2021 Jul 22.
Nat Cancer. 2021.
PMID: 35122027
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