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Antitumor activity without on-target off-tumor toxicity of GD2-chimeric antigen receptor T cells in patients with neuroblastoma.
Straathof K, Flutter B, Wallace R, Jain N, Loka T, Depani S, Wright G, Thomas S, Cheung GW, Gileadi T, Stafford S, Kokalaki E, Barton J, Marriott C, Rampling D, Ogunbiyi O, Akarca AU, Marafioti T, Inglott S, Gilmour K, Al-Hajj M, Day W, McHugh K, Biassoni L, Sizer N, Barton C, Edwards D, Dragoni I, Silvester J, Dyer K, Traub S, Elson L, Brook S, Westwood N, Robson L, Bedi A, Howe K, Barry A, Duncan C, Barone G, Pule M, Anderson J. Straathof K, et al. Among authors: barton j, barton c. Sci Transl Med. 2020 Nov 25;12(571):eabd6169. doi: 10.1126/scitranslmed.abd6169. Sci Transl Med. 2020. PMID: 33239386
Engineered human mesenchymal stem cells for neuroblastoma therapeutics.
Nieddu V, Piredda R, Bexell D, Barton J, Anderson J, Sebire N, Kolluri K, Janes SM, Karteris E, Sala A. Nieddu V, et al. Among authors: barton j. Oncol Rep. 2019 Jul;42(1):35-42. doi: 10.3892/or.2019.7152. Epub 2019 May 8. Oncol Rep. 2019. PMID: 31115546 Free PMC article.
A tailored molecular profiling programme for children with cancer to identify clinically actionable genetic alterations.
George SL, Izquierdo E, Campbell J, Koutroumanidou E, Proszek P, Jamal S, Hughes D, Yuan L, Marshall LV, Carceller F, Chisholm JC, Vaidya S, Mandeville H, Angelini P, Wasti A, Bexelius T, Thway K, Gatz SA, Clarke M, Al-Lazikani B, Barone G, Anderson J, Tweddle DA, Gonzalez D, Walker BA, Barton J, Depani S, Eze J, Ahmed SW, Moreno L, Pearson A, Shipley J, Jones C, Hargrave D, Jacques TS, Hubank M, Chesler L. George SL, et al. Among authors: barton j. Eur J Cancer. 2019 Nov;121:224-235. doi: 10.1016/j.ejca.2019.07.027. Epub 2019 Sep 19. Eur J Cancer. 2019. PMID: 31543384 Free PMC article.
A Promyelocytic Leukemia Protein-Thrombospondin-2 Axis and the Risk of Relapse in Neuroblastoma.
Dvorkina M, Nieddu V, Chakelam S, Pezzolo A, Cantilena S, Leite AP, Chayka O, Regad T, Pistorio A, Sementa AR, Virasami A, Barton J, Montano X, Lechertier T, Brindle N, Morgenstern D, Lebras M, Burns AJ, Saunders NJ, Hodivala-Dilke K, Bagella L, De The H, Anderson J, Sebire N, Pistoia V, Sala A, Salomoni P. Dvorkina M, et al. Among authors: barton j. Clin Cancer Res. 2016 Jul 1;22(13):3398-409. doi: 10.1158/1078-0432.CCR-15-2081. Epub 2016 Apr 13. Clin Cancer Res. 2016. PMID: 27076624
Signatures of recent activation identify a circulating T cell compartment containing tumor-specific antigen receptors with high avidity.
Purcarea A, Jarosch S, Barton J, Grassmann S, Pachmayr L, D'Ippolito E, Hammel M, Hochholzer A, Wagner KI, van den Berg JH, Buchholz VR, Haanen JBAG, Busch DH, Schober K. Purcarea A, et al. Among authors: barton j. Sci Immunol. 2022 Aug 12;7(74):eabm2077. doi: 10.1126/sciimmunol.abm2077. Epub 2022 Aug 12. Sci Immunol. 2022. PMID: 35960818
Long-term persistence and functionality of adoptively transferred antigen-specific T cells with genetically ablated PD-1 expression.
Dötsch S, Svec M, Schober K, Hammel M, Wanisch A, Gökmen F, Jarosch S, Warmuth L, Barton J, Cicin-Sain L, D'Ippolito E, Busch DH. Dötsch S, et al. Among authors: barton j. Proc Natl Acad Sci U S A. 2023 Mar 7;120(10):e2200626120. doi: 10.1073/pnas.2200626120. Epub 2023 Feb 28. Proc Natl Acad Sci U S A. 2023. PMID: 36853939 Free PMC article.
2,100 results