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Modeling plasticity and dysplasia of pancreatic ductal organoids derived from human pluripotent stem cells.
Breunig M, Merkle J, Wagner M, Melzer MK, Barth TFE, Engleitner T, Krumm J, Wiedenmann S, Cohrs CM, Perkhofer L, Jain G, Krüger J, Hermann PC, Schmid M, Madácsy T, Varga Á, Griger J, Azoitei N, Müller M, Wessely O, Robey PG, Heller S, Dantes Z, Reichert M, Günes C, Bolenz C, Kuhn F, Maléth J, Speier S, Liebau S, Sipos B, Kuster B, Seufferlein T, Rad R, Meier M, Hohwieler M, Kleger A. Breunig M, et al. Among authors: barth tfe. Cell Stem Cell. 2021 Jun 3;28(6):1105-1124.e19. doi: 10.1016/j.stem.2021.03.005. Epub 2021 Apr 28. Cell Stem Cell. 2021. PMID: 33915078 Free PMC article.
A rare cause of upper GI bleeding and wasting disease.
van Erp RJ, Schröppel B, Barth TF, Seufferlein T, Schmidt SA, Meining A, Kleger A. van Erp RJ, et al. Gut. 2016 May;65(5):787, 881. doi: 10.1136/gutjnl-2015-310404. Epub 2015 Oct 28. Gut. 2016. PMID: 26511796 No abstract available.
YAP Activation Drives Liver Regeneration after Cholestatic Damage Induced by Rbpj Deletion.
Tharehalli U, Svinarenko M, Kraus JM, Kühlwein SD, Szekely R, Kiesle U, Scheffold A, Barth TFE, Kleger A, Schirmbeck R, Kestler HA, Seufferlein T, Oswald F, Katz SF, Lechel A. Tharehalli U, et al. Among authors: barth tfe. Int J Mol Sci. 2018 Nov 29;19(12):3801. doi: 10.3390/ijms19123801. Int J Mol Sci. 2018. PMID: 30501048 Free PMC article.
Pancreatic cancer-derived organoids - a disease modeling tool to predict drug response.
Frappart PO, Walter K, Gout J, Beutel AK, Morawe M, Arnold F, Breunig M, Barth TF, Marienfeld R, Schulte L, Ettrich T, Hackert T, Svinarenko M, Rösler R, Wiese S, Wiese H, Perkhofer L, Müller M, Lechel A, Sainz B Jr, Hermann PC, Seufferlein T, Kleger A. Frappart PO, et al. United European Gastroenterol J. 2020 Jun;8(5):594-606. doi: 10.1177/2050640620905183. Epub 2020 Feb 19. United European Gastroenterol J. 2020. PMID: 32213029 Free PMC article.
Drug Inhibition of SARS-CoV-2 Replication in Human Pluripotent Stem Cell-Derived Intestinal Organoids.
Krüger J, Groß R, Conzelmann C, Müller JA, Koepke L, Sparrer KMJ, Weil T, Schütz D, Seufferlein T, Barth TFE, Stenger S, Heller S, Münch J, Kleger A. Krüger J, et al. Among authors: barth tfe. Cell Mol Gastroenterol Hepatol. 2021;11(4):935-948. doi: 10.1016/j.jcmgh.2020.11.003. Epub 2020 Nov 10. Cell Mol Gastroenterol Hepatol. 2021. PMID: 33186749 Free PMC article.
SARS-CoV-2 infects and replicates in cells of the human endocrine and exocrine pancreas.
Müller JA, Groß R, Conzelmann C, Krüger J, Merle U, Steinhart J, Weil T, Koepke L, Bozzo CP, Read C, Fois G, Eiseler T, Gehrmann J, van Vuuren J, Wessbecher IM, Frick M, Costa IG, Breunig M, Grüner B, Peters L, Schuster M, Liebau S, Seufferlein T, Stenger S, Stenzinger A, MacDonald PE, Kirchhoff F, Sparrer KMJ, Walther P, Lickert H, Barth TFE, Wagner M, Münch J, Heller S, Kleger A. Müller JA, et al. Among authors: barth tfe. Nat Metab. 2021 Feb;3(2):149-165. doi: 10.1038/s42255-021-00347-1. Epub 2021 Feb 3. Nat Metab. 2021. PMID: 33536639
A Prospective Feasibility Trial to Challenge Patient-Derived Pancreatic Cancer Organoids in Predicting Treatment Response.
Beutel AK, Schütte L, Scheible J, Roger E, Müller M, Perkhofer L, Kestler AMTU, Kraus JM, Kestler HA, Barth TFE, Lemke J, Kornmann M, Ettrich TJ, Gout J, Seufferlein T, Kleger A. Beutel AK, et al. Among authors: barth tfe. Cancers (Basel). 2021 May 21;13(11):2539. doi: 10.3390/cancers13112539. Cancers (Basel). 2021. PMID: 34064221 Free PMC article.
294 results