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Cell Type-Specific Intralocus Interactions Reveal Oligodendrocyte Mechanisms in MS.
Factor DC, Barbeau AM, Allan KC, Hu LR, Madhavan M, Hoang AT, Hazel KEA, Hall PA, Nisraiyya S, Najm FJ, Miller TE, Nevin ZS, Karl RT, Lima BR, Song Y, Sibert AG, Dhillon GK, Volsko C, Bartels CF, Adams DJ, Dutta R, Gallagher MD, Phu W, Kozlenkov A, Dracheva S, Scacheri PC, Tesar PJ, Corradin O. Factor DC, et al. Among authors: bartels cf. Cell. 2020 Apr 16;181(2):382-395.e21. doi: 10.1016/j.cell.2020.03.002. Epub 2020 Apr 3. Cell. 2020. PMID: 32246942 Free PMC article.
Non-canonical Targets of HIF1a Impair Oligodendrocyte Progenitor Cell Function.
Allan KC, Hu LR, Scavuzzo MA, Morton AR, Gevorgyan AS, Cohn EF, Clayton BLL, Bederman IR, Hung S, Bartels CF, Madhavan M, Tesar PJ. Allan KC, et al. Among authors: bartels cf. Cell Stem Cell. 2021 Feb 4;28(2):257-272.e11. doi: 10.1016/j.stem.2020.09.019. Epub 2020 Oct 21. Cell Stem Cell. 2021. PMID: 33091368 Free PMC article.
Epigenomic enhancer profiling defines a signature of colon cancer.
Akhtar-Zaidi B, Cowper-Sal-lari R, Corradin O, Saiakhova A, Bartels CF, Balasubramanian D, Myeroff L, Lutterbaugh J, Jarrar A, Kalady MF, Willis J, Moore JH, Tesar PJ, Laframboise T, Markowitz S, Lupien M, Scacheri PC. Akhtar-Zaidi B, et al. Among authors: bartels cf. Science. 2012 May 11;336(6082):736-9. doi: 10.1126/science.1217277. Epub 2012 Apr 12. Science. 2012. PMID: 22499810 Free PMC article.
Functional Enhancers Shape Extrachromosomal Oncogene Amplifications.
Morton AR, Dogan-Artun N, Faber ZJ, MacLeod G, Bartels CF, Piazza MS, Allan KC, Mack SC, Wang X, Gimple RC, Wu Q, Rubin BP, Shetty S, Angers S, Dirks PB, Sallari RC, Lupien M, Rich JN, Scacheri PC. Morton AR, et al. Among authors: bartels cf. Cell. 2019 Nov 27;179(6):1330-1341.e13. doi: 10.1016/j.cell.2019.10.039. Epub 2019 Nov 21. Cell. 2019. PMID: 31761532 Free PMC article.
Robust Hi-C Maps of Enhancer-Promoter Interactions Reveal the Function of Non-coding Genome in Neural Development and Diseases.
Lu L, Liu X, Huang WK, Giusti-Rodríguez P, Cui J, Zhang S, Xu W, Wen Z, Ma S, Rosen JD, Xu Z, Bartels CF, Kawaguchi R, Hu M, Scacheri PC, Rong Z, Li Y, Sullivan PF, Song H, Ming GL, Li Y, Jin F. Lu L, et al. Among authors: bartels cf. Mol Cell. 2020 Aug 6;79(3):521-534.e15. doi: 10.1016/j.molcel.2020.06.007. Epub 2020 Jun 26. Mol Cell. 2020. PMID: 32592681 Free PMC article.
Convergence of case-specific epigenetic alterations identify a confluence of genetic vulnerabilities tied to opioid overdose.
Corradin O, Sallari R, Hoang AT, Kassim BS, Ben Hutta G, Cuoto L, Quach BC, Lovrenert K, Hays C, Gryder BE, Iskhakova M, Cates H, Song Y, Bartels CF, Hancock DB, Mash DC, Johnson EO, Akbarian S, Scacheri PC. Corradin O, et al. Among authors: bartels cf. Mol Psychiatry. 2022 Apr;27(4):2158-2170. doi: 10.1038/s41380-022-01477-y. Epub 2022 Mar 17. Mol Psychiatry. 2022. PMID: 35301427 Free PMC article.
CHD7 targets active gene enhancer elements to modulate ES cell-specific gene expression.
Schnetz MP, Handoko L, Akhtar-Zaidi B, Bartels CF, Pereira CF, Fisher AG, Adams DJ, Flicek P, Crawford GE, Laframboise T, Tesar P, Wei CL, Scacheri PC. Schnetz MP, et al. Among authors: bartels cf. PLoS Genet. 2010 Jul 15;6(7):e1001023. doi: 10.1371/journal.pgen.1001023. PLoS Genet. 2010. PMID: 20657823 Free PMC article.
Hotspots of aberrant enhancer activity punctuate the colorectal cancer epigenome.
Cohen AJ, Saiakhova A, Corradin O, Luppino JM, Lovrenert K, Bartels CF, Morrow JJ, Mack SC, Dhillon G, Beard L, Myeroff L, Kalady MF, Willis J, Bradner JE, Keri RA, Berger NA, Pruett-Miller SM, Markowitz SD, Scacheri PC. Cohen AJ, et al. Among authors: bartels cf. Nat Commun. 2017 Feb 7;8:14400. doi: 10.1038/ncomms14400. Nat Commun. 2017. PMID: 28169291 Free PMC article.
Ex vivo screen identifies CDK12 as a metastatic vulnerability in osteosarcoma.
Bayles I, Krajewska M, Pontius WD, Saiakhova A, Morrow JJ, Bartels C, Lu J, Faber ZJ, Fedorov Y, Hong ES, Karnuta JM, Rubin B, Adams DJ, George RE, Scacheri PC. Bayles I, et al. J Clin Invest. 2019 Oct 1;129(10):4377-4392. doi: 10.1172/JCI127718. J Clin Invest. 2019. PMID: 31498151 Free PMC article.
68 results