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Discovery of Orally Available and Brain Penetrant AEP Inhibitors.
Krummenacher D, He W, Kuhn B, Schnider C, Beurier A, Brom V, Sivasothy T, Marty C, Tosstorff A, Hewings DS, Mesch S, Pinard E, Brändlin M, Hochstrasser R, Westwood P, Rothe J, Kronenberger A, Morandi F, Gutbier S, Schuler A, Heer D, Gloria LE, Joedicke L, Rudolph MG, Müller L, Grüninger F, Baumann K, Kaniyappan S, Manevski N, Bartels B. Krummenacher D, et al. Among authors: bartels b. J Med Chem. 2023 Dec 28;66(24):17026-17043. doi: 10.1021/acs.jmedchem.3c01804. Epub 2023 Dec 13. J Med Chem. 2023. PMID: 38090813
Selective and brain-penetrant HCN1 inhibitors reveal links between synaptic integration, cortical function, and working memory.
Harde E, Hierl M, Weber M, Waiz D, Wyler R, Wach JY, Haab R, Gundlfinger A, He W, Schnider P, Paina M, Rolland JF, Greiter-Wilke A, Gasser R, Reutlinger M, Dupont A, Roberts S, O'Connor EC, Bartels B, Hall BJ. Harde E, et al. Among authors: bartels b. Cell Chem Biol. 2024 Mar 21;31(3):577-592.e23. doi: 10.1016/j.chembiol.2023.11.004. Epub 2023 Dec 1. Cell Chem Biol. 2024. PMID: 38042151 Free article.
Enhanced low-threshold motor unit capacity during endurance tasks in patients with spinal muscular atrophy using pyridostigmine.
Habets LE, Bartels B, Jeneson JAL, Asselman FL, Stam M, Wijngaarde CA, Wadman RI, van Eijk RPA, Stegeman DF, Ludo van der Pol W. Habets LE, et al. Among authors: bartels b. Clin Neurophysiol. 2023 Oct;154:100-106. doi: 10.1016/j.clinph.2023.06.024. Epub 2023 Jul 20. Clin Neurophysiol. 2023. PMID: 37595479 Free article. Clinical Trial.
80 results