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SARS-CoV-2 infects adipose tissue in a fat depot- and viral lineage-dependent manner.
Saccon TD, Mousovich-Neto F, Ludwig RG, Carregari VC, Dos Anjos Souza AB, Dos Passos ASC, Martini MC, Barbosa PP, de Souza GF, Muraro SP, Forato J, Amorim MR, Marques RE, Veras FP, Barreto E, Gonçalves TT, Paiva IM, Fazolini NPB, Onodera CMK, Martins Junior RB, de Araújo PHC, Batah SS, Viana RMM, de Melo DM, Fabro AT, Arruda E, Queiroz Cunha F, Cunha TM, Pretti MAM, Smith BJ, Marques-Souza H, Knittel TL, Ruiz GP, Profeta GS, Fontes-Cal TCM, Boroni M, Vinolo MAR, Farias AS, Moraes-Vieira PMM, Bizzacchi JMA, Teesalu T, Chaim FDM, Cazzo E, Chaim EA, Proença-Módena JL, Martins-de-Souza D, Osako MK, Leiria LO, Mori MA. Saccon TD, et al. Among authors: barreto e. Nat Commun. 2022 Sep 29;13(1):5722. doi: 10.1038/s41467-022-33218-8. Nat Commun. 2022. PMID: 36175400 Free PMC article.
Simvastatin Downregulates the SARS-CoV-2-Induced Inflammatory Response and Impairs Viral Infection Through Disruption of Lipid Rafts.
Teixeira L, Temerozo JR, Pereira-Dutra FS, Ferreira AC, Mattos M, Gonçalves BS, Sacramento CQ, Palhinha L, Cunha-Fernandes T, Dias SSG, Soares VC, Barreto EA, Cesar-Silva D, Fintelman-Rodrigues N, Pão CRR, de Freitas CS, Reis PA, Hottz ED, Bozza FA, Bou-Habib DC, Saraiva EM, de Almeida CJG, Viola JPB, Souza TML, Bozza PT. Teixeira L, et al. Front Immunol. 2022 Feb 18;13:820131. doi: 10.3389/fimmu.2022.820131. eCollection 2022. Front Immunol. 2022. PMID: 35251001 Free PMC article.
COVID-19-related hyperglycemia is associated with infection of hepatocytes and stimulation of gluconeogenesis.
Barreto EA, Cruz AS, Veras FP, Martins R, Bernardelli RS, Paiva IM, Lima TM, Singh Y, Guimarães RC, Damasceno S, Pereira N, Alves JM, Gonçalves TT, Forato J, Muraro SP, Souza GF, Batah SS, Proenca-Modena JL, Mori MA, Cunha FQ, Louzada-Junior P, Cunha TM, Nakaya HI, Fabro A, de Oliveira RDR, Arruda E, Réa R, Réa Neto Á, Fernandes da Silva MM, Leiria LO. Barreto EA, et al. Proc Natl Acad Sci U S A. 2023 May 23;120(21):e2217119120. doi: 10.1073/pnas.2217119120. Epub 2023 May 15. Proc Natl Acad Sci U S A. 2023. PMID: 37186819 Free PMC article.
Lipid droplets fuel SARS-CoV-2 replication and production of inflammatory mediators.
Dias SSG, Soares VC, Ferreira AC, Sacramento CQ, Fintelman-Rodrigues N, Temerozo JR, Teixeira L, Nunes da Silva MA, Barreto E, Mattos M, de Freitas CS, Azevedo-Quintanilha IG, Manso PPA, Miranda MD, Siqueira MM, Hottz ED, Pão CRR, Bou-Habib DC, Barreto-Vieira DF, Bozza FA, Souza TML, Bozza PT. Dias SSG, et al. Among authors: barreto vieira df, barreto e. PLoS Pathog. 2020 Dec 16;16(12):e1009127. doi: 10.1371/journal.ppat.1009127. eCollection 2020 Dec. PLoS Pathog. 2020. PMID: 33326472 Free PMC article.
SARS-CoV-2 engages inflammasome and pyroptosis in human primary monocytes.
Ferreira AC, Soares VC, de Azevedo-Quintanilha IG, Dias SDSG, Fintelman-Rodrigues N, Sacramento CQ, Mattos M, de Freitas CS, Temerozo JR, Teixeira L, Damaceno Hottz E, Barreto EA, Pão CRR, Palhinha L, Miranda M, Bou-Habib DC, Bozza FA, Bozza PT, Souza TML. Ferreira AC, et al. Among authors: barreto ea. Cell Death Discov. 2021 Mar 1;7(1):43. doi: 10.1038/s41420-021-00428-w. Cell Death Discov. 2021. PMID: 33649297 Free PMC article.
Correction: SARS-CoV-2 engages inflammasome and pyroptosis in human primary monocytes.
Ferreira AC, Soares VC, de Azevedo-Quintanilha IG, Dias SDSG, Fintelman-Rodrigues N, Sacramento CQ, Mattos M, de Freitas CS, Temerozo JR, Teixeira L, Hottz ED, Barreto EA, Pão CRR, Palhinha L, Miranda M, Bou-Habib DC, Bozza FA, Bozza PT, Souza TML. Ferreira AC, et al. Cell Death Discov. 2021 May 19;7(1):116. doi: 10.1038/s41420-021-00477-1. Cell Death Discov. 2021. PMID: 34011951 Free PMC article. No abstract available.
Prevention of lipid droplet accumulation by DGAT1 inhibition ameliorates sepsis-induced liver injury and inflammation.
Teixeira L, Pereira-Dutra FS, Reis PA, Cunha-Fernandes T, Yoshinaga MY, Souza-Moreira L, Souza EK, Barreto EA, Silva TP, Espinheira-Silva H, Igreja T, Antunes MM, Bombaça ACS, Gonçalves-de-Albuquerque CF, Menezes GB, Hottz ED, Menna-Barreto RFS, Maya-Monteiro CM, Bozza FA, Miyamoto S, Melo RCN, Bozza PT. Teixeira L, et al. JHEP Rep. 2023 Dec 11;6(2):100984. doi: 10.1016/j.jhepr.2023.100984. eCollection 2024 Feb. JHEP Rep. 2023. PMID: 38293685 Free PMC article.
Macroevolution of the plant-hummingbird pollination system.
Barreto E, Boehm MMA, Ogutcen E, Abrahamczyk S, Kessler M, Bascompte J, Dellinger AS, Bello C, Dehling DM, Duchenne F, Kaehler M, Lagomarsino LP, Lohmann LG, Maglianesi MA, Morlon H, Muchhala N, Ornelas JF, Perret M, Salinas NR, Smith SD, Vamosi JC, Varassin IG, Graham CH. Barreto E, et al. Biol Rev Camb Philos Soc. 2024 May 5. doi: 10.1111/brv.13094. Online ahead of print. Biol Rev Camb Philos Soc. 2024. PMID: 38705863
361 results