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Extremely potent pan-sarbecovirus neutralizing antibodies generated by immunization of macaques with an AS03-adjuvanted monovalent subunit vaccine against SARS-CoV-2.
Feng Y, Yuan M, Powers JM, Hu M, Munt JE, Arunachalam PS, Leist SR, Bellusci L, Adams LE, Sundaramurthy S, Shirreff LM, Mallory ML, Scooby TD, Moreno A, O'Hagan DT, Kleanthous H, Villinger FJ, Veesler D, King NP, Suthar MS, Khurana S, Baric RS, Wilson IA, Pulendran B. Feng Y, et al. Among authors: baric rs. bioRxiv [Preprint]. 2023 Jan 20:2023.01.19.524784. doi: 10.1101/2023.01.19.524784. bioRxiv. 2023. PMID: 36711543 Free PMC article. Preprint.
Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccines.
Walls AC, Miranda MC, Pham MN, Schäfer A, Greaney A, Arunachalam PS, Navarro MJ, Tortorici MA, Rogers K, O'Connor MA, Shireff L, Ferrell DE, Brunette N, Kepl E, Bowen J, Zepeda SK, Starr T, Hsieh CL, Fiala B, Wrenn S, Pettie D, Sydeman C, Johnson M, Blackstone A, Ravichandran R, Ogohara C, Carter L, Tilles SW, Rappuoli R, O'Hagan DT, Van Der Most R, Van Voorhis WC, McLellan JS, Kleanthous H, Sheahan TP, Fuller DH, Villinger F, Bloom J, Pulendran B, Baric R, King N, Veesler D. Walls AC, et al. bioRxiv [Preprint]. 2021 Mar 16:2021.03.15.435528. doi: 10.1101/2021.03.15.435528. bioRxiv. 2021. PMID: 33758839 Free PMC article. Updated. Preprint.
SARS-CoV-2 Vaccines Elicit Durable Immune Responses in Infant Rhesus Macaques.
Garrido C, Curtis AD, Dennis M, Pathak SH, Gao H, Montefiori D, Tomai M, Fox CB, Kozlowski PA, Scobey T, Munt JE, Mallroy ML, Saha PT, Hudgens MG, Lindesmith LC, Baric RS, Abiona OM, Graham B, Corbett KS, Edwards D, Carfi A, Fouda G, Van Rompay KKA, De Paris K, Permar SR. Garrido C, et al. Among authors: baric rs. bioRxiv [Preprint]. 2021 Apr 6:2021.04.05.438479. doi: 10.1101/2021.04.05.438479. bioRxiv. 2021. PMID: 33851156 Free PMC article. Updated. Preprint.
Common Mechanism of SARS-CoV and SARS-CoV-2 Pathogenesis across Species.
Schäfer A, Gralinski LE, Leist SR, Winkler ES, Hampton BK, Mooney MA, Jensen KL, Graham RL, Agnihothram S, Jeng S, Chamberlin S, Bell TA, Scobey DT, VanBlargan LA, Thackray LB, Hock P, Miller DR, Shaw GD, de Villena FPM, McWeeney SK, Montgomery SA, Diamond MS, Heise MT, Menachery VD, Ferris MT, Baric RS. Schäfer A, et al. Among authors: baric rs. bioRxiv [Preprint]. 2021 May 14:2021.05.14.444205. doi: 10.1101/2021.05.14.444205. bioRxiv. 2021. PMID: 34013261 Free PMC article. Preprint.
Protective efficacy of rhesus adenovirus COVID-19 vaccines against mouse-adapted SARS-CoV-2.
Tostanoski LH, Gralinski LE, Martinez DR, Schaefer A, Mahrokhian SH, Li Z, Nampanya F, Wan H, Yu J, Chang A, Liu J, McMahan K, Dinnon KH, Leist SR, Baric RS, Barouch DH. Tostanoski LH, et al. Among authors: baric rs. bioRxiv [Preprint]. 2021 Jun 15:2021.06.14.448461. doi: 10.1101/2021.06.14.448461. bioRxiv. 2021. PMID: 34159335 Free PMC article. Updated. Preprint.
Targeted isolation of panels of diverse human protective broadly neutralizing antibodies against SARS-like viruses.
He WT, Musharrafieh R, Song G, Dueker K, Tse LV, Martinez DR, Schäfer A, Callaghan S, Yong P, Beutler N, Torres JL, Volk RM, Zhou P, Yuan M, Liu H, Anzanello F, Capozzola T, Parren M, Garcia E, Rawlings SA, Smith DM, Wilson IA, Safonova Y, Ward AB, Rogers TF, Baric RS, Gralinski LE, Burton DR, Andrabi R. He WT, et al. Among authors: baric rs. bioRxiv [Preprint]. 2022 Feb 8:2021.09.08.459480. doi: 10.1101/2021.09.08.459480. bioRxiv. 2022. PMID: 35169804 Free PMC article. Updated. Preprint.
A model of persistent post SARS-CoV-2 induced lung disease for target identification and testing of therapeutic strategies.
Dinnon KH 3rd, Leist SR, Okuda K, Dang H, Fritch EJ, Gully KL, De la Cruz G, Evangelista MD, Asakura T, Gilmore RC, Hawkins P, Nakano S, West A, Schäfer A, Gralinski LE, Everman JL, Sajuthi SP, Zweigart MR, Dong S, McBride J, Cooley MR, Hines JB, Love MK, Groshong SD, VanSchoiack A, Phelan SJ, Liang Y, Hether T, Leon M, Zumwalt RE, Barton LM, Duval EJ, Mukhopadhyay S, Stroberg E, Borczuk A, Thorne LB, Sakthivel MK, Lee YZ, Hagood JS, Mock JR, Seibold MA, O'Neal WK, Montgomery SA, Boucher RC, Baric RS. Dinnon KH 3rd, et al. Among authors: baric rs. bioRxiv [Preprint]. 2022 Feb 15:2022.02.15.480515. doi: 10.1101/2022.02.15.480515. bioRxiv. 2022. PMID: 35194605 Free PMC article. Preprint.
Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause severe disease.
Zhou P, Song G, He WT, Beutler N, Tse LV, Martinez DR, Schäfer A, Anzanello F, Yong P, Peng L, Dueker K, Musharrafieh R, Callaghan S, Capozzola T, Yuan M, Liu H, Limbo O, Parren M, Garcia E, Rawlings SA, Smith DM, Nemazee D, Jardine JG, Wilson IA, Safonova Y, Rogers TF, Baric RS, Gralinski LE, Burton DR, Andrabi R. Zhou P, et al. Among authors: baric rs. bioRxiv [Preprint]. 2022 Mar 7:2022.03.04.479488. doi: 10.1101/2022.03.04.479488. bioRxiv. 2022. PMID: 35291291 Free PMC article. Updated. Preprint.
Dynamics of SARS-CoV-2 VOC neutralization and novel mAb reveal protection against Omicron.
Hao L, Hsiang TY, Dalmat RR, Ireton R, Morton J, Stokes C, Netland J, Hale M, Thouvenel C, Wald A, Franko NM, Huden K, Chu H, Greninger A, Tilles S, Barrett LK, Van Voorhis WC, Munt J, Scobey T, Baric RS, Rawlings D, Pepper M, Drain PK, Gale M. Hao L, et al. Among authors: baric rs. medRxiv [Preprint]. 2022 Aug 16:2022.08.12.22278720. doi: 10.1101/2022.08.12.22278720. medRxiv. 2022. PMID: 36032965 Free PMC article. Updated. Preprint.
Fc mediated pan-sarbecovirus protection after alphavirus vector vaccination.
Adams LE, Leist SR, Dinnon KH, West A, Gully KL, Anderson EJ, Loome JF, Madden EA, Powers JM, Schäfer A, Sarkar S, Castillo IN, Maron JS, McNamara RP, Bertera HL, Zweigert MR, Higgins JS, Hampton BK, Premkumar L, Alter G, Montgomery SA, Baxter VK, Heise MT, Baric RS. Adams LE, et al. Among authors: baric rs. bioRxiv [Preprint]. 2022 Nov 28:2022.11.28.518175. doi: 10.1101/2022.11.28.518175. bioRxiv. 2022. PMID: 36482964 Free PMC article. Updated. Preprint.
544 results