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Computer-aided engineering of a branching sucrase for the glucodiversification of a tetrasaccharide precursor of S. flexneri antigenic oligosaccharides.
Sci Rep. 2021 Oct 13;11(1):20294. doi: 10.1038/s41598-021-99384-9.
Sci Rep. 2021.
PMID: 34645865
Free PMC article.
Convergent Chemoenzymatic Strategy to Deliver a Diversity of Shigella flexneri Serotype-Specific O-Antigen Segments from a Unique Lightly Protected Tetrasaccharide Core.
Hu Z, Benkoulouche M, Barel LA, Le Heiget G, Ben Imeddourene A, Le Guen Y, Monties N, Guerreiro C, Remaud-Siméon M, Moulis C, André I, Mulard LA.
Hu Z, et al. Among authors: barel la.
J Org Chem. 2021 Feb 5;86(3):2058-2075. doi: 10.1021/acs.joc.0c00777.
J Org Chem. 2021.
PMID: 32700907
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Redirecting substrate regioselectivity using engineered ΔN123-GBD-CD2 branching sucrases for the production of pentasaccharide repeating units of S. flexneri 3a, 4a and 4b haptens.
Benkoulouche M, Ben Imeddourene A, Barel LA, Le Heiget G, Pizzut S, Kulyk H, Bellvert F, Bozonnet S, Mulard LA, Remaud-Siméon M, Moulis C, André I.
Benkoulouche M, et al. Among authors: barel la.
Sci Rep. 2021 Jan 28;11(1):2474. doi: 10.1038/s41598-021-81719-1.
Sci Rep. 2021.
PMID: 33510212
Free PMC article.
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Classical and novel strategies to develop a Shigella glycoconjugate vaccine: from concept to efficacy in human.
Barel LA, Mulard LA.
Barel LA, et al.
Hum Vaccin Immunother. 2019;15(6):1338-1356. doi: 10.1080/21645515.2019.1606972.
Hum Vaccin Immunother. 2019.
PMID: 31158047
Free PMC article.
Review.
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Identification of a mechanism promoting mitochondrial sterol accumulation during myocardial ischemia-reperfusion: role of TSPO and STAR.
Bréhat J, Leick S, Musman J, Su JB, Eychenne N, Giton F, Rivard M, Barel LA, Tropeano C, Vitarelli F, Caccia C, Leoni V, Ghaleh B, Pons S, Morin D.
Bréhat J, et al. Among authors: barel la.
Basic Res Cardiol. 2024 Mar 22. doi: 10.1007/s00395-024-01043-3. Online ahead of print.
Basic Res Cardiol. 2024.
PMID: 38517482
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Development of carbon monoxide-releasing molecules conjugated to polysaccharides (glyco-CORMs) for delivering CO during obesity.
Mohan S, Barel LA, Benrahla DE, Do B, Mao Q, Kitagishi H, Rivard M, Motterlini R, Foresti R.
Mohan S, et al. Among authors: barel la.
Pharmacol Res. 2023 May;191:106770. doi: 10.1016/j.phrs.2023.106770. Epub 2023 Apr 15.
Pharmacol Res. 2023.
PMID: 37068532
Free article.
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