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Genomic characterisation of Eμ-Myc mouse lymphomas identifies Bcor as a Myc co-operative tumour-suppressor gene.
Lefebure M, Tothill RW, Kruse E, Hawkins ED, Shortt J, Matthews GM, Gregory GP, Martin BP, Kelly MJ, Todorovski I, Doyle MA, Lupat R, Li J, Schroeder J, Wall M, Craig S, Poortinga G, Cameron D, Bywater M, Kats L, Gearhart MD, Bardwell VJ, Dickins RA, Hannan RD, Papenfuss AT, Johnstone RW. Lefebure M, et al. Among authors: bardwell vj. Nat Commun. 2017 Mar 6;8:14581. doi: 10.1038/ncomms14581. Nat Commun. 2017. PMID: 28262675 Free PMC article.
Bcor loss perturbs myeloid differentiation and promotes leukaemogenesis.
Kelly MJ, So J, Rogers AJ, Gregory G, Li J, Zethoven M, Gearhart MD, Bardwell VJ, Johnstone RW, Vervoort SJ, Kats LM. Kelly MJ, et al. Among authors: bardwell vj. Nat Commun. 2019 Mar 22;10(1):1347. doi: 10.1038/s41467-019-09250-6. Nat Commun. 2019. PMID: 30902969 Free PMC article.
Loss of function mutations of BCOR in classical Hodgkin lymphoma.
Giefing M, Gearhart MD, Schneider M, Overbeck B, Klapper W, Hartmann S, Ustaszewski A, Weniger MA, Wiehle L, Hansmann ML, Melnick A, Béguelin W, Sundström C, Küppers R, Bardwell VJ, Siebert R. Giefing M, et al. Among authors: bardwell vj. Leuk Lymphoma. 2022 May;63(5):1080-1090. doi: 10.1080/10428194.2021.2015587. Epub 2021 Dec 27. Leuk Lymphoma. 2022. PMID: 34957890
BCOR regulates myeloid cell proliferation and differentiation.
Cao Q, Gearhart MD, Gery S, Shojaee S, Yang H, Sun H, Lin DC, Bai JW, Mead M, Zhao Z, Chen Q, Chien WW, Alkan S, Alpermann T, Haferlach T, Müschen M, Bardwell VJ, Koeffler HP. Cao Q, et al. Among authors: bardwell vj. Leukemia. 2016 May;30(5):1155-65. doi: 10.1038/leu.2016.2. Epub 2016 Feb 5. Leukemia. 2016. PMID: 26847029 Free PMC article.
Sexual cell-fate reprogramming in the ovary by DMRT1.
Lindeman RE, Gearhart MD, Minkina A, Krentz AD, Bardwell VJ, Zarkower D. Lindeman RE, et al. Among authors: bardwell vj. Curr Biol. 2015 Mar 16;25(6):764-771. doi: 10.1016/j.cub.2015.01.034. Epub 2015 Feb 12. Curr Biol. 2015. PMID: 25683803 Free PMC article.
65 results