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The genomic landscape of Mexican Indigenous populations brings insights into the peopling of the Americas.
García-Ortiz H, Barajas-Olmos F, Contreras-Cubas C, Cid-Soto MÁ, Córdova EJ, Centeno-Cruz F, Mendoza-Caamal E, Cicerón-Arellano I, Flores-Huacuja M, Baca P, Bolnick DA, Snow M, Flores-Martínez SE, Ortiz-Lopez R, Reynolds AW, Blanchet A, Morales-Marín M, Velázquez-Cruz R, Kostic AD, Galaviz-Hernández C, García-Zapién AG, Jiménez-López JC, León-Reyes G, Salas-Bautista EG, Lazalde-Ramos BP, Jiménez-Ruíz JL, Salas-Martínez G, Ramos-Madrigal J, Mirzaeicheshmeh E, Saldaña-Alvarez Y, Del Carmen Abrahantes-Pérez M, Loeza-Becerra F, Mojica-Espinosa R, Sánchez-Quinto F, Rangel-Villalobos H, Sosa-Macías M, Sánchez-Corona J, Rojas-Martinez A, Martínez-Hernández A, Orozco L. García-Ortiz H, et al. Nat Commun. 2021 Oct 12;12(1):5942. doi: 10.1038/s41467-021-26188-w. Nat Commun. 2021. PMID: 34642312 Free PMC article.
Gene variants in AKT1, GCKR and SOCS3 are differentially associated with metabolic traits in Mexican Amerindians and Mestizos.
Cid-Soto MA, Martínez-Hernández A, García-Ortíz H, Córdova EJ, Barajas-Olmos F, Centeno-Cruz F, Contreras-Cubas C, Mendoza-Caamal EC, Ciceron-Arellano I, Morales-Rivera MI, Jimenez-Ruiz JL, Salas-Martínez G, Saldaña-Álvarez Y, Revilla-Monsalve C, Islas-Andrade S, Orozco L. Cid-Soto MA, et al. Gene. 2018 Dec 30;679:160-171. doi: 10.1016/j.gene.2018.08.076. Epub 2018 Aug 31. Gene. 2018. PMID: 30176313
Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls.
Flannick J, Mercader JM, Fuchsberger C, Udler MS, Mahajan A, Wessel J, Teslovich TM, Caulkins L, Koesterer R, Barajas-Olmos F, Blackwell TW, Boerwinkle E, Brody JA, Centeno-Cruz F, Chen L, Chen S, Contreras-Cubas C, Córdova E, Correa A, Cortes M, DeFronzo RA, Dolan L, Drews KL, Elliott A, Floyd JS, Gabriel S, Garay-Sevilla ME, García-Ortiz H, Gross M, Han S, Heard-Costa NL, Jackson AU, Jørgensen ME, Kang HM, Kelsey M, Kim BJ, Koistinen HA, Kuusisto J, Leader JB, Linneberg A, Liu CT, Liu J, Lyssenko V, Manning AK, Marcketta A, Malacara-Hernandez JM, Martínez-Hernández A, Matsuo K, Mayer-Davis E, Mendoza-Caamal E, Mohlke KL, Morrison AC, Ndungu A, Ng MCY, O'Dushlaine C, Payne AJ, Pihoker C; Broad Genomics Platform; Post WS, Preuss M, Psaty BM, Vasan RS, Rayner NW, Reiner AP, Revilla-Monsalve C, Robertson NR, Santoro N, Schurmann C, So WY, Soberón X, Stringham HM, Strom TM, Tam CHT, Thameem F, Tomlinson B, Torres JM, Tracy RP, van Dam RM, Vujkovic M, Wang S, Welch RP, Witte DR, Wong TY, Atzmon G, Barzilai N, Blangero J, Bonnycastle LL, Bowden DW, Chambers JC, Chan E, Cheng CY, Cho YS, Collins FS, de Vries PS, Duggirala R, Glaser B, Gonzalez C, Gonzalez ME, Groop L, Kooner JS, Kwak SH… See abstract for full author list ➔ Flannick J, et al. Nature. 2019 Jun;570(7759):71-76. doi: 10.1038/s41586-019-1231-2. Epub 2019 May 22. Nature. 2019. PMID: 31118516 Free PMC article.
Catalytically Impaired TYK2 Variants are Protective Against Childhood- and Adult-Onset Systemic Lupus Erythematosus in Mexicans.
Contreras-Cubas C, García-Ortiz H, Velázquez-Cruz R, Barajas-Olmos F, Baca P, Martínez-Hernández A, Barbosa-Cobos RE, Ramírez-Bello J, López-Hernández MA, Svyryd Y, Mutchinick OM, Baca V, Orozco L. Contreras-Cubas C, et al. Sci Rep. 2019 Aug 21;9(1):12165. doi: 10.1038/s41598-019-48451-3. Sci Rep. 2019. PMID: 31434951 Free PMC article.
Variation in Actionable Pharmacogenetic Markers in Natives and Mestizos From Mexico.
Gonzalez-Covarrubias V, Morales-Franco M, Cruz-Correa OF, Martínez-Hernández A, García-Ortíz H, Barajas-Olmos F, Genis-Mendoza AD, Martínez-Magaña JJ, Nicolini H, Orozco L, Soberón X. Gonzalez-Covarrubias V, et al. Front Pharmacol. 2019 Oct 10;10:1169. doi: 10.3389/fphar.2019.01169. eCollection 2019. Front Pharmacol. 2019. PMID: 31649539 Free PMC article.
Genetic variability of five ADRB2 polymorphisms among Mexican Amerindian ethnicities and the Mestizo population.
Salas-Martínez MG, Saldaña-Alvarez Y, Cordova EJ, Mendiola-Soto DK, Cid-Soto MA, Luckie-Duque A, Vicenteño-Ayala H, Barajas-Olmos F, Contreras-Cubas C, García-Ortiz H, Jiménez-Ruíz JL, Centeno-Cruz F, Martínez-Hernández A, Mendoza-Caamal EC, Mirzaeicheshmeh E, Orozco L. Salas-Martínez MG, et al. PLoS One. 2019 Dec 2;14(12):e0225030. doi: 10.1371/journal.pone.0225030. eCollection 2019. PLoS One. 2019. PMID: 31790415 Free PMC article.
41 results