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Page 1
Sarcoma treatment in the era of molecular medicine.
Grünewald TG, Alonso M, Avnet S, Banito A, Burdach S, Cidre-Aranaz F, Di Pompo G, Distel M, Dorado-Garcia H, Garcia-Castro J, González-González L, Grigoriadis AE, Kasan M, Koelsche C, Krumbholz M, Lecanda F, Lemma S, Longo DL, Madrigal-Esquivel C, Morales-Molina Á, Musa J, Ohmura S, Ory B, Pereira-Silva M, Perut F, Rodriguez R, Seeling C, Al Shaaili N, Shaabani S, Shiavone K, Sinha S, Tomazou EM, Trautmann M, Vela M, Versleijen-Jonkers YM, Visgauss J, Zalacain M, Schober SJ, Lissat A, English WR, Baldini N, Heymann D. Grünewald TG, et al. Among authors: banito a. EMBO Mol Med. 2020 Nov 6;12(11):e11131. doi: 10.15252/emmm.201911131. Epub 2020 Oct 13. EMBO Mol Med. 2020. PMID: 33047515 Free PMC article. Review.
Molecular characteristics and therapeutic vulnerabilities across paediatric solid tumours.
Jones DTW, Banito A, Grünewald TGP, Haber M, Jäger N, Kool M, Milde T, Molenaar JJ, Nabbi A, Pugh TJ, Schleiermacher G, Smith MA, Westermann F, Pfister SM. Jones DTW, et al. Among authors: banito a. Nat Rev Cancer. 2019 Aug;19(8):420-438. doi: 10.1038/s41568-019-0169-x. Epub 2019 Jul 12. Nat Rev Cancer. 2019. PMID: 31300807 Review.
Endometrial stromal sarcomas with BCOR-rearrangement harbor MDM2 amplifications.
Kommoss FK, Chang KT, Stichel D, Banito A, Jones DT, Heilig CE, Fröhling S, Sahm F, Stenzinger A, Hartmann W, Mechtersheimer G, Sinn HP, Schmidt D, Kommoss F, von Deimling A, Koelsche C. Kommoss FK, et al. Among authors: banito a. J Pathol Clin Res. 2020 Jul;6(3):178-184. doi: 10.1002/cjp2.165. Epub 2020 Apr 30. J Pathol Clin Res. 2020. PMID: 32352245 Free PMC article.
Therapeutic targeting of the PLK1-PRC1-axis triggers cell death in genomically silent childhood cancer.
Li J, Ohmura S, Marchetto A, Orth MF, Imle R, Dallmayer M, Musa J, Knott MML, Hölting TLB, Stein S, Funk CM, Sastre A, Alonso J, Bestvater F, Kasan M, Romero-Pérez L, Hartmann W, Ranft A, Banito A, Dirksen U, Kirchner T, Cidre-Aranaz F, Grünewald TGP. Li J, et al. Among authors: banito a. Nat Commun. 2021 Sep 16;12(1):5356. doi: 10.1038/s41467-021-25553-z. Nat Commun. 2021. PMID: 34531368 Free PMC article.
Integrative gene network and functional analyses identify a prognostically relevant key regulator of metastasis in Ewing sarcoma.
Cidre-Aranaz F, Li J, Hölting TLB, Orth MF, Imle R, Kutschmann S, Ammirati G, Ceranski K, Carreño-Gonzalez MJ, Kasan M, Marchetto A, Funk CM, Bestvater F, Bersini S, Arrigoni C, Moretti M, Thiel U, Baumhoer D, Sahm F, Pfister SM, Hartmann W, Dirksen U, Romero-Pérez L, Banito A, Ohmura S, Musa J, Kirchner T, Knott MML, Grünewald TGP. Cidre-Aranaz F, et al. Among authors: banito a. Mol Cancer. 2022 Jan 3;21(1):1. doi: 10.1186/s12943-021-01470-z. Mol Cancer. 2022. PMID: 34980141 Free PMC article. No abstract available.
Multi-omic and functional analysis for classification and treatment of sarcomas with FUS-TFCP2 or EWSR1-TFCP2 fusions.
Schöpf J, Uhrig S, Heilig CE, Lee KS, Walther T, Carazzato A, Dobberkau AM, Weichenhan D, Plass C, Hartmann M, Diwan GD, Carrero ZI, Ball CR, Hohl T, Kindler T, Rudolph-Hähnel P, Helm D, Schneider M, Nilsson A, Øra I, Imle R, Banito A, Russell RB, Jones BC, Lipka DB, Glimm H, Hübschmann D, Hartmann W, Fröhling S, Scholl C. Schöpf J, et al. Among authors: banito a. Nat Commun. 2024 Jan 2;15(1):51. doi: 10.1038/s41467-023-44360-2. Nat Commun. 2024. PMID: 38168093 Free PMC article.
Functional Therapeutic Target Validation Using Pediatric Zebrafish Xenograft Models.
Gatzweiler C, Ridinger J, Herter S, Gerloff XF, ElHarouni D, Berker Y, Imle R, Schmitt L, Kreth S, Stainczyk S, Ayhan S, Najafi S, Krunic D, Frese K, Meder B, Reuss D, Fiesel P, Schramm K, Blattner-Johnson M, Jones DTW, Banito A, Westermann F, Oppermann S, Milde T, Peterziel H, Witt O, Oehme I. Gatzweiler C, et al. Among authors: banito a. Cancers (Basel). 2022 Feb 8;14(3):849. doi: 10.3390/cancers14030849. Cancers (Basel). 2022. PMID: 35159116 Free PMC article.
Aberrant gene activation in synovial sarcoma relies on SSX specificity and increased PRC1.1 stability.
Benabdallah NS, Dalal V, Scott RW, Marcous F, Sotiriou A, Kommoss FKF, Pejkovska A, Gaspar L, Wagner L, Sánchez-Rivera FJ, Ta M, Thornton S, Nielsen TO, Underhill TM, Banito A. Benabdallah NS, et al. Among authors: banito a. Nat Struct Mol Biol. 2023 Nov;30(11):1640-1652. doi: 10.1038/s41594-023-01096-3. Epub 2023 Sep 21. Nat Struct Mol Biol. 2023. PMID: 37735617 Free PMC article.
40 results