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Synthesis and Biological Evaluation of New Antitubulin Agents Containing 2-(3',4',5'-trimethoxyanilino)-3,6-disubstituted-4,5,6,7-tetrahydrothieno[2,3-c]pyridine Scaffold.
Romagnoli R, Prencipe F, Oliva P, Cacciari B, Balzarini J, Liekens S, Hamel E, Brancale A, Ferla S, Manfredini S, Zurlo M, Finotti A, Gambari R. Romagnoli R, et al. Among authors: balzarini j. Molecules. 2020 Apr 7;25(7):1690. doi: 10.3390/molecules25071690. Molecules. 2020. PMID: 32272719 Free PMC article.
Design, synthesis, and biological evaluation of thiophene analogues of chalcones.
Romagnoli R, Baraldi PG, Carrion MD, Cara CL, Cruz-Lopez O, Preti D, Tolomeo M, Grimaudo S, Di Cristina A, Zonta N, Balzarini J, Brancale A, Sarkar T, Hamel E. Romagnoli R, et al. Among authors: balzarini j. Bioorg Med Chem. 2008 May 15;16(10):5367-76. doi: 10.1016/j.bmc.2008.04.026. Epub 2008 Apr 15. Bioorg Med Chem. 2008. PMID: 18440234
Synthesis and biological evaluation of 2-amino-3-(3',4',5'-trimethoxybenzoyl)-6-substituted-4,5,6,7-tetrahydrothieno[2,3-c]pyridine derivatives as antimitotic agents and inhibitors of tubulin polymerization.
Romagnoli R, Baraldi PG, Carrion MD, Cruz-Lopez O, Cara CL, Tolomeo M, Grimaudo S, Di Cristina A, Pipitone MR, Balzarini J, Kandil S, Brancale A, Sarkar T, Hamel E. Romagnoli R, et al. Among authors: balzarini j. Bioorg Med Chem Lett. 2008 Sep 15;18(18):5041-5. doi: 10.1016/j.bmcl.2008.08.006. Epub 2008 Aug 6. Bioorg Med Chem Lett. 2008. PMID: 18725179 Free PMC article.
Design, synthesis and biological evaluation of 3,5-disubstituted 2-amino thiophene derivatives as a novel class of antitumor agents.
Romagnoli R, Baraldi PG, Lopez-Cara C, Salvador MK, Preti D, Tabrizi MA, Balzarini J, Nussbaumer P, Bassetto M, Brancale A, Fu XH, Yang-Gao, Li J, Zhang SZ, Hamel E, Bortolozzi R, Basso G, Viola G. Romagnoli R, et al. Among authors: balzarini j. Bioorg Med Chem. 2014 Sep 15;22(18):5097-109. doi: 10.1016/j.bmc.2013.12.030. Epub 2013 Dec 24. Bioorg Med Chem. 2014. PMID: 24398384 Free PMC article.
2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition.
Romagnoli R, Kimatrai Salvador M, Schiaffino Ortega S, Baraldi PG, Oliva P, Baraldi S, Lopez-Cara LC, Brancale A, Ferla S, Hamel E, Balzarini J, Liekens S, Mattiuzzo E, Basso G, Viola G. Romagnoli R, et al. Among authors: balzarini j. Eur J Med Chem. 2018 Jan 1;143:683-698. doi: 10.1016/j.ejmech.2017.11.096. Eur J Med Chem. 2018. PMID: 29220790 Free PMC article.
Design, synthesis and biological evaluation of 2-alkoxycarbonyl-3-anilinoindoles as a new class of potent inhibitors of tubulin polymerization.
Romagnoli R, Prencipe F, Oliva P, Kimatrai Salvador M, Brancale A, Ferla S, Hamel E, Viola G, Bortolozzi R, Persoons L, Balzarini J, Liekens S, Schols D. Romagnoli R, et al. Among authors: balzarini j. Bioorg Chem. 2020 Apr;97:103665. doi: 10.1016/j.bioorg.2020.103665. Epub 2020 Feb 18. Bioorg Chem. 2020. PMID: 32086053 Free article.
Synthesis and biological evaluation of 2- and 3-aminobenzo[b]thiophene derivatives as antimitotic agents and inhibitors of tubulin polymerization.
Romagnoli R, Baraldi PG, Carrion MD, Lopez Cara C, Preti D, Fruttarolo F, Pavani MG, Tabrizi MA, Tolomeo M, Grimaudo S, Di Cristina A, Balzarini J, Hadfield JA, Brancale A, Hamel E. Romagnoli R, et al. Among authors: balzarini j. J Med Chem. 2007 May 3;50(9):2273-7. doi: 10.1021/jm070050f. Epub 2007 Apr 10. J Med Chem. 2007. PMID: 17419607
1,242 results