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SGLT2 inhibitor ertugliflozin decreases elevated intracellular sodium, and improves energetics and contractile function in diabetic cardiomyopathy.
Croteau D, Baka T, Young S, He H, Chambers JM, Qin F, Panagia M, Pimentel DR, Balschi JA, Colucci WS, Luptak I. Croteau D, et al. Among authors: balschi ja. Biomed Pharmacother. 2023 Apr;160:114310. doi: 10.1016/j.biopha.2023.114310. Epub 2023 Jan 31. Biomed Pharmacother. 2023. PMID: 36731341 Free PMC article.
Energetic Dysfunction Is Mediated by Mitochondrial Reactive Oxygen Species and Precedes Structural Remodeling in Metabolic Heart Disease.
Luptak I, Qin F, Sverdlov AL, Pimentel DR, Panagia M, Croteau D, Siwik DA, Bachschmid MM, He H, Balschi JA, Colucci WS. Luptak I, et al. Among authors: balschi ja. Antioxid Redox Signal. 2019 Sep 1;31(7):539-549. doi: 10.1089/ars.2018.7707. Epub 2019 Jun 25. Antioxid Redox Signal. 2019. PMID: 31088291 Free PMC article.
Decreased ATP production and myocardial contractile reserve in metabolic heart disease.
Luptak I, Sverdlov AL, Panagia M, Qin F, Pimentel DR, Croteau D, Siwik DA, Ingwall JS, Bachschmid MM, Balschi JA, Colucci WS. Luptak I, et al. Among authors: balschi ja. J Mol Cell Cardiol. 2018 Mar;116:106-114. doi: 10.1016/j.yjmcc.2018.01.017. Epub 2018 Feb 1. J Mol Cell Cardiol. 2018. PMID: 29409987 Free PMC article.
Cardiac-specific VLCAD deficiency induces dilated cardiomyopathy and cold intolerance.
Xiong D, He H, James J, Tokunaga C, Powers C, Huang Y, Osinska H, Towbin JA, Purevjav E, Balschi JA, Javadov S, McGowan FX Jr, Strauss AW, Khuchua Z. Xiong D, et al. Among authors: balschi ja. Am J Physiol Heart Circ Physiol. 2014 Feb;306(3):H326-38. doi: 10.1152/ajpheart.00931.2012. Epub 2013 Nov 27. Am J Physiol Heart Circ Physiol. 2014. PMID: 24285112 Free PMC article.
52 results