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LKB1-SIK2 loss drives uveal melanoma proliferation and hypersensitivity to SLC8A1 and ROS inhibition.
Proteau S, Krossa I, Husser C, Guéguinou M, Sella F, Bille K, Irondelle M, Dalmasso M, Barouillet T, Cheli Y, Pisibon C, Arrighi N, Nahon-Estève S, Martel A, Gastaud L, Lassalle S, Mignen O, Brest P, Mazure NM, Bost F, Baillif S, Landreville S, Turcotte S, Hasson D, Carcamo S, Vandier C, Bernstein E, Yvan-Charvet L, Levesque MP, Ballotti R, Bertolotto C, Strub T. Proteau S, et al. Among authors: ballotti r. EMBO Mol Med. 2023 Dec 7;15(12):e17719. doi: 10.15252/emmm.202317719. Epub 2023 Nov 15. EMBO Mol Med. 2023. PMID: 37966164 Free PMC article.
Deregulated MITF sumoylation: A route to melanoma.
Ballotti R, Bertolotto C. Ballotti R, et al. Mol Cell Oncol. 2017 May 26;4(4):e1331154. doi: 10.1080/23723556.2017.1331154. eCollection 2017. Mol Cell Oncol. 2017. PMID: 28868345 Free PMC article.
Single-cell RNA sequencing reveals intratumoral heterogeneity in primary uveal melanomas and identifies HES6 as a driver of the metastatic disease.
Pandiani C, Strub T, Nottet N, Cheli Y, Gambi G, Bille K, Husser C, Dalmasso M, Béranger G, Lassalle S, Magnone V, Pédeutour F, Irondelle M, Maschi C, Nahon-Estève S, Martel A, Caujolle JP, Hofman P, LeBrigand K, Davidson I, Baillif S, Barbry P, Ballotti R, Bertolotto C. Pandiani C, et al. Among authors: ballotti r. Cell Death Differ. 2021 Jun;28(6):1990-2000. doi: 10.1038/s41418-020-00730-7. Epub 2021 Jan 18. Cell Death Differ. 2021. PMID: 33462406 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 33563928
Recent advances in understanding the role of HES6 in cancers.
Krossa I, Strub T, Martel A, Nahon-Esteve S, Lassalle S, Hofman P, Baillif S, Ballotti R, Bertolotto C. Krossa I, et al. Among authors: ballotti r. Theranostics. 2022 May 20;12(9):4374-4385. doi: 10.7150/thno.72966. eCollection 2022. Theranostics. 2022. PMID: 35673577 Free PMC article. Review.
Lysine Methyltransferase NSD1 and Cancers: Any Role in Melanoma?
Krossa I, Strub T, Aplin AE, Ballotti R, Bertolotto C. Krossa I, et al. Among authors: ballotti r. Cancers (Basel). 2022 Oct 5;14(19):4865. doi: 10.3390/cancers14194865. Cancers (Basel). 2022. PMID: 36230787 Free PMC article. Review.
164 results