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Lysosomal calcium regulates autophagy.
Medina DL, Ballabio A. Medina DL, et al. Among authors: ballabio a. Autophagy. 2015;11(6):970-1. doi: 10.1080/15548627.2015.1047130. Autophagy. 2015. PMID: 26000950 Free PMC article. Review.
Exploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis.
Sergin I, Evans TD, Zhang X, Bhattacharya S, Stokes CJ, Song E, Ali S, Dehestani B, Holloway KB, Micevych PS, Javaheri A, Crowley JR, Ballabio A, Schilling JD, Epelman S, Weihl CC, Diwan A, Fan D, Zayed MA, Razani B. Sergin I, et al. Among authors: ballabio a. Nat Commun. 2017 Jun 7;8:15750. doi: 10.1038/ncomms15750. Nat Commun. 2017. PMID: 28589926 Free PMC article.
Enhanced lysosomal degradation maintains the quiescent state of neural stem cells.
Kobayashi T, Piao W, Takamura T, Kori H, Miyachi H, Kitano S, Iwamoto Y, Yamada M, Imayoshi I, Shioda S, Ballabio A, Kageyama R. Kobayashi T, et al. Among authors: ballabio a. Nat Commun. 2019 Nov 29;10(1):5446. doi: 10.1038/s41467-019-13203-4. Nat Commun. 2019. PMID: 31784517 Free PMC article.
Loss of the batten disease protein CLN3 leads to mis-trafficking of M6PR and defective autophagic-lysosomal reformation.
Calcagni' A, Staiano L, Zampelli N, Minopoli N, Herz NJ, Di Tullio G, Huynh T, Monfregola J, Esposito A, Cirillo C, Bajic A, Zahabiyon M, Curnock R, Polishchuk E, Parkitny L, Medina DL, Pastore N, Cullen PJ, Parenti G, De Matteis MA, Grumati P, Ballabio A. Calcagni' A, et al. Among authors: ballabio a. Nat Commun. 2023 Jul 3;14(1):3911. doi: 10.1038/s41467-023-39643-7. Nat Commun. 2023. PMID: 37400440 Free PMC article.
455 results