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Repurposing Atovaquone as a Therapeutic against Acute Myeloid Leukemia (AML): Combination with Conventional Chemotherapy Is Feasible and Well Tolerated.
Stevens AM, Schafer ES, Li M, Terrell M, Rashid R, Paek H, Bernhardt MB, Weisnicht A, Smith WT, Keogh NJ, Alozie MC, Oviedo HH, Gonzalez AK, Ilangovan T, Mangubat-Medina A, Wang H, Jo E, Rabik CA, Bocchini C, Hilsenbeck S, Ball ZT, Cooper TM, Redell MS. Stevens AM, et al. Among authors: ball zt. Cancers (Basel). 2023 Feb 20;15(4):1344. doi: 10.3390/cancers15041344. Cancers (Basel). 2023. PMID: 36831684 Free PMC article.
Assessing the intracellular fate of rhodium(ii) complexes.
Minus MB, Kang MK, Knudsen SE, Liu W, Krueger MJ, Smith ML, Redell MS, Ball ZT. Minus MB, et al. Among authors: ball zt. Chem Commun (Camb). 2016 Sep 22;52(78):11685-11688. doi: 10.1039/c6cc05192h. Chem Commun (Camb). 2016. PMID: 27709185 Free PMC article.
Rapid nickel(ii)-promoted cysteine S-arylation with arylboronic acids.
Hanaya K , Ohata J , Miller MK , Mangubat-Medina AE , Swierczynski MJ , Yang DC , Rosenthal RM , Popp BV , Ball ZT . Hanaya K , et al. Among authors: ball zt. Chem Commun (Camb). 2019 Feb 28;55(19):2841-2844. doi: 10.1039/c9cc00159j. Chem Commun (Camb). 2019. PMID: 30768093
Atovaquone is active against AML by upregulating the integrated stress pathway and suppressing oxidative phosphorylation.
Stevens AM, Xiang M, Heppler LN, Tošić I, Jiang K, Munoz JO, Gaikwad AS, Horton TM, Long X, Narayanan P, Seashore EL, Terrell MC, Rashid R, Krueger MJ, Mangubat-Medina AE, Ball ZT, Sumazin P, Walker SR, Hamada Y, Oyadomari S, Redell MS, Frank DA. Stevens AM, et al. Among authors: ball zt. Blood Adv. 2019 Dec 23;3(24):4215-4227. doi: 10.1182/bloodadvances.2019000499. Blood Adv. 2019. PMID: 31856268 Free PMC article.
Red-shifted backbone N-H photocaging agents.
Mangubat-Medina AE, Trial HO, Vargas RD, Setegne MT, Bader T, Distefano MD, Ball ZT. Mangubat-Medina AE, et al. Among authors: ball zt. Org Biomol Chem. 2020 Jul 15;18(27):5110-5114. doi: 10.1039/d0ob00923g. Org Biomol Chem. 2020. PMID: 32519726
74 results