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The palmitoylation of gasdermin D directs its membrane translocation and pore formation during pyroptosis.
Balasubramanian A, Hsu AY, Ghimire L, Tahir M, Devant P, Fontana P, Du G, Liu X, Fabin D, Kambara H, Xie X, Liu F, Hasegawa T, Xu R, Yu H, Chen M, Kolakowski S, Trauger S, Larsen MR, Wei W, Wu H, Kagan JC, Lieberman J, Luo HR. Balasubramanian A, et al. Sci Immunol. 2024 Apr 12;9(94):eadn1452. doi: 10.1126/sciimmunol.adn1452. Epub 2024 Apr 12. Sci Immunol. 2024. PMID: 38530158
ROS-dependent S-palmitoylation activates cleaved and intact gasdermin D.
Du G, Healy LB, David L, Walker C, El-Baba TJ, Lutomski CA, Goh B, Gu B, Pi X, Devant P, Fontana P, Dong Y, Ma X, Miao R, Balasubramanian A, Puthenveetil R, Banerjee A, Luo HR, Kagan JC, Oh SF, Robinson CV, Lieberman J, Wu H. Du G, et al. Among authors: balasubramanian a. Nature. 2024 Apr 10. doi: 10.1038/s41586-024-07373-5. Online ahead of print. Nature. 2024. PMID: 38599239
Impact of automated data flow and reminders on adherence and resource utilization for remotely monitoring physical activity in individuals with stroke or chronic obstructive pulmonary disease.
French MA, Balasubramanian A, Hansel NN, Penttinen SK, Wise R, Raghavan P, Wegener ST, Roemmich RT, Celnik PA. French MA, et al. Among authors: balasubramanian a. medRxiv [Preprint]. 2024 Apr 18:2024.04.15.24305852. doi: 10.1101/2024.04.15.24305852. medRxiv. 2024. PMID: 38699312 Free PMC article. Preprint.
A multicenter, randomized, double-blind, placebo-controlled ascending dose study to evaluate the safety, tolerability, pharmacokinetics (PK) and pharmacodynamic (PD) effects of Posiphen in subjects with Early Alzheimer's Disease.
Galasko D, Farlow MR, Lucey BP, Honig LS, Elbert D, Bateman R, Momper J, Thomas R, Rissman RA, Pa J, Aslanyan V, Balasubramanian A, West T, Maccecchini M, Feldman HH. Galasko D, et al. Among authors: balasubramanian a. medRxiv [Preprint]. 2024 Mar 22:2024.03.20.24304638. doi: 10.1101/2024.03.20.24304638. medRxiv. 2024. PMID: 38562783 Free PMC article. Preprint.
Integrative spatial omics reveals distinct tumor-promoting multicellular niches and immunosuppressive mechanisms in African American and European American patients with TNBC.
Zhu Q, Balasubramanian A, Asirvatham JR, Piyarathna DWB, Kaur J, Mohamed N, Wu L, Chatterjee M, Wang S, Pourfarrokh N, Rasaily U, Xu Y, Zheng J, Jebakumar D, Rao A, Chen SH, Li Y, Chang E, Li X, Aneja R, Zhang XH, Sreekumar A. Zhu Q, et al. Among authors: balasubramanian a. bioRxiv [Preprint]. 2024 Mar 31:2024.03.17.585428. doi: 10.1101/2024.03.17.585428. bioRxiv. 2024. PMID: 38562769 Free PMC article. Preprint.
465 results