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Induction of APOBEC3 Exacerbates DNA Replication Stress and Chromosomal Instability in Early Breast and Lung Cancer Evolution.
Venkatesan S, Angelova M, Puttick C, Zhai H, Caswell DR, Lu WT, Dietzen M, Galanos P, Evangelou K, Bellelli R, Lim EL, Watkins TBK, Rowan A, Teixeira VH, Zhao Y, Chen H, Ngo B, Zalmas LP, Al Bakir M, Hobor S, Grönroos E, Pennycuick A, Nigro E, Campbell BB, Brown WL, Akarca AU, Marafioti T, Wu MY, Howell M, Boulton SJ, Bertoli C, Fenton TR, de Bruin RAM, Maya-Mendoza A, Santoni-Rugiu E, Hynds RE, Gorgoulis VG, Jamal-Hanjani M, McGranahan N, Harris RS, Janes SM, Bartkova J, Bakhoum SF, Bartek J, Kanu N, Swanton C; TRACERx Consortium. Venkatesan S, et al. Among authors: bakhoum sf. Cancer Discov. 2021 Oct;11(10):2456-2473. doi: 10.1158/2159-8290.CD-20-0725. Epub 2021 May 4. Cancer Discov. 2021. PMID: 33947663 Free PMC article.
Chromosomal instability, aneuploidy, and cancer.
Bakhoum SF, Swanton C. Bakhoum SF, et al. Front Oncol. 2014 Jun 19;4:161. doi: 10.3389/fonc.2014.00161. eCollection 2014. Front Oncol. 2014. PMID: 24995162 Free PMC article. No abstract available.
Chromosomal instability drives metastasis through a cytosolic DNA response.
Bakhoum SF, Ngo B, Laughney AM, Cavallo JA, Murphy CJ, Ly P, Shah P, Sriram RK, Watkins TBK, Taunk NK, Duran M, Pauli C, Shaw C, Chadalavada K, Rajasekhar VK, Genovese G, Venkatesan S, Birkbak NJ, McGranahan N, Lundquist M, LaPlant Q, Healey JH, Elemento O, Chung CH, Lee NY, Imielenski M, Nanjangud G, Pe'er D, Cleveland DW, Powell SN, Lammerding J, Swanton C, Cantley LC. Bakhoum SF, et al. Nature. 2018 Jan 25;553(7689):467-472. doi: 10.1038/nature25432. Epub 2018 Jan 17. Nature. 2018. PMID: 29342134 Free PMC article.
75 results