Baker TS - Search Results

1

B-cell epitopes: Discontinuity and conformational analysis.

Ferdous S, Kelm S, Baker TS, Shi J, Martin ACR. Ferdous S, et al. Among authors: baker ts. Mol Immunol. 2019 Oct;114:643-650. doi: 10.1016/j.molimm.2019.09.014. Epub 2019 Sep 20. Mol Immunol. 2019. PMID: 31546099

2

Antibody i-Patch prediction of the antibody binding site improves rigid local antibody-antigen docking.

Krawczyk K, Baker T, Shi J, Deane CM. Krawczyk K, et al. Protein Eng Des Sel. 2013 Oct;26(10):621-9. doi: 10.1093/protein/gzt043. Epub 2013 Sep 4. Protein Eng Des Sel. 2013. PMID: 24006373

3

SAbDab: the structural antibody database.

Dunbar J, Krawczyk K, Leem J, Baker T, Fuchs A, Georges G, Shi J, Deane CM. Dunbar J, et al. Nucleic Acids Res. 2014 Jan;42(Database issue):D1140-6. doi: 10.1093/nar/gkt1043. Epub 2013 Nov 8. Nucleic Acids Res. 2014. PMID: 24214988 Free PMC article.

4

Improving B-cell epitope prediction and its application to global antibody-antigen docking.

Krawczyk K, Liu X, Baker T, Shi J, Deane CM. Krawczyk K, et al. Bioinformatics. 2014 Aug 15;30(16):2288-94. doi: 10.1093/bioinformatics/btu190. Epub 2014 Apr 21. Bioinformatics. 2014. PMID: 24753488 Free PMC article.

5

Length-independent structural similarities enrich the antibody CDR canonical class model.

Nowak J, Baker T, Georges G, Kelm S, Klostermann S, Shi J, Sridharan S, Deane CM. Nowak J, et al. MAbs. 2016 May-Jun;8(4):751-60. doi: 10.1080/19420862.2016.1158370. MAbs. 2016. PMID: 26963563 Free PMC article.

6

Computational design of an epitope-specific Keap1 binding antibody using hotspot residues grafting and CDR loop swapping.

Liu X, Taylor RD, Griffin L, Coker SF, Adams R, Ceska T, Shi J, Lawson AD, Baker T. Liu X, et al. Sci Rep. 2017 Jan 27;7:41306. doi: 10.1038/srep41306. Sci Rep. 2017. PMID: 28128368 Free PMC article.

7

Membrane Interactions of α-Synuclein Revealed by Multiscale Molecular Dynamics Simulations, Markov State Models, and NMR.

Amos STA, Schwarz TC, Shi J, Cossins BP, Baker TS, Taylor RJ, Konrat R, Sansom MSP. Amos STA, et al. Among authors: baker ts. J Phys Chem B. 2021 Mar 25;125(11):2929-2941. doi: 10.1021/acs.jpcb.1c01281. Epub 2021 Mar 15. J Phys Chem B. 2021. PMID: 33719460 Free PMC article.

8

Higher Affinity Antibodies Bind With Lower Hydration and Flexibility in Large Scale Simulations.

Wong MTY, Kelm S, Liu X, Taylor RD, Baker T, Essex JW. Wong MTY, et al. Front Immunol. 2022 May 30;13:884110. doi: 10.3389/fimmu.2022.884110. eCollection 2022. Front Immunol. 2022. PMID: 35707541 Free PMC article.

9

Corrigendum: Higher Affinity Antibodies Bind With Lower Hydration and Flexibility in Large Scale Simulations.

Wong MTY, Kelm S, Liu X, Taylor RD, Baker T, Essex JW. Wong MTY, et al. Front Immunol. 2022 Jul 4;13:969176. doi: 10.3389/fimmu.2022.969176. eCollection 2022. Front Immunol. 2022. PMID: 35860259 Free PMC article.

10

Epitope determines efficacy of therapeutic anti-Tau antibodies in a functional assay with human Alzheimer Tau.

Courade JP, Angers R, Mairet-Coello G, Pacico N, Tyson K, Lightwood D, Munro R, McMillan D, Griffin R, Baker T, Starkie D, Nan R, Westwood M, Mushikiwabo ML, Jung S, Odede G, Sweeney B, Popplewell A, Burgess G, Downey P, Citron M. Courade JP, et al. Acta Neuropathol. 2018 Nov;136(5):729-745. doi: 10.1007/s00401-018-1911-2. Epub 2018 Sep 20. Acta Neuropathol. 2018. PMID: 30238240 Free PMC article.

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