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Discovery of V-0219: A Small-Molecule Positive Allosteric Modulator of the Glucagon-Like Peptide-1 Receptor toward Oral Treatment for "Diabesity".
Decara JM, Vázquez-Villa H, Brea J, Alonso M, Srivastava RK, Orio L, Alén F, Suárez J, Baixeras E, García-Cárceles J, Escobar-Peña A, Lutz B, Rodríguez R, Codesido E, Garcia-Ladona FJ, Bennett TA, Ballesteros JA, Cruces J, Loza MI, Benhamú B, Rodríguez de Fonseca F, López-Rodríguez ML. Decara JM, et al. Among authors: baixeras e. J Med Chem. 2022 Apr 14;65(7):5449-5461. doi: 10.1021/acs.jmedchem.1c01842. Epub 2022 Mar 29. J Med Chem. 2022. PMID: 35349261 Free PMC article.
Adiponectin promoter activator NP-1 reduces body weight and hepatic steatosis in high-fat diet-fed animals.
Serrano A, Pavón FJ, Suarez J, Rivera P, Vida M, Bermúdez-Silva FJ, Alonso M, Martínez A, López-Ogalla J, Alonso-Gascón M, Santamaría G, Romero-Cuevas M, Pérez-Valero V, Baixeras E, Rodríguez de Fonseca F. Serrano A, et al. Among authors: baixeras e. Am J Physiol Endocrinol Metab. 2012 Apr 1;302(7):E817-30. doi: 10.1152/ajpendo.00468.2011. Epub 2012 Jan 31. Am J Physiol Endocrinol Metab. 2012. PMID: 22297300 Free article.
Oleoylethanolamide enhances β-adrenergic-mediated thermogenesis and white-to-brown adipocyte phenotype in epididymal white adipose tissue in rat.
Suárez J, Rivera P, Arrabal S, Crespillo A, Serrano A, Baixeras E, Pavón FJ, Cifuentes M, Nogueiras R, Ballesteros J, Dieguez C, Rodríguez de Fonseca F. Suárez J, et al. Among authors: baixeras e. Dis Model Mech. 2014 Jan;7(1):129-41. doi: 10.1242/dmm.013110. Epub 2013 Oct 23. Dis Model Mech. 2014. PMID: 24159189 Free PMC article.
CB1 blockade potentiates down-regulation of lipogenic gene expression in perirenal adipose tissue in high carbohydrate diet-induced obesity.
Vida M, Rivera P, Gavito AL, Suárez J, Pavón FJ, Arrabal S, Romero-Cuevas M, Bautista D, Martínez A, de Fonseca FR, Serrano A, Baixeras E. Vida M, et al. Among authors: baixeras e. PLoS One. 2014 Feb 25;9(2):e90016. doi: 10.1371/journal.pone.0090016. eCollection 2014. PLoS One. 2014. PMID: 24587189 Free PMC article.
Plasma profile of pro-inflammatory cytokines and chemokines in cocaine users under outpatient treatment: influence of cocaine symptom severity and psychiatric co-morbidity.
Araos P, Pedraz M, Serrano A, Lucena M, Barrios V, García-Marchena N, Campos-Cloute R, Ruiz JJ, Romero P, Suárez J, Baixeras E, de la Torre R, Montesinos J, Guerri C, Rodríguez-Arias M, Miñarro J, Martínez-Riera R, Torrens M, Chowen JA, Argente J, Mason BJ, Pavón FJ, Rodríguez de Fonseca F. Araos P, et al. Among authors: baixeras e. Addict Biol. 2015 Jul;20(4):756-72. doi: 10.1111/adb.12156. Epub 2014 May 22. Addict Biol. 2015. PMID: 24854157
Chronic administration of recombinant IL-6 upregulates lipogenic enzyme expression and aggravates high-fat-diet-induced steatosis in IL-6-deficient mice.
Vida M, Gavito AL, Pavón FJ, Bautista D, Serrano A, Suarez J, Arrabal S, Decara J, Romero-Cuevas M, Rodríguez de Fonseca F, Baixeras E. Vida M, et al. Among authors: baixeras e. Dis Model Mech. 2015 Jul 1;8(7):721-31. doi: 10.1242/dmm.019166. Epub 2015 May 14. Dis Model Mech. 2015. PMID: 26035386 Free PMC article.
Role of the satiety factor oleoylethanolamide in alcoholism.
Bilbao A, Serrano A, Cippitelli A, Pavón FJ, Giuffrida A, Suárez J, García-Marchena N, Baixeras E, Gómez de Heras R, Orio L, Alén F, Ciccocioppo R, Cravatt BF, Parsons LH, Piomelli D, Rodríguez de Fonseca F. Bilbao A, et al. Among authors: baixeras e. Addict Biol. 2016 Jul;21(4):859-72. doi: 10.1111/adb.12276. Epub 2015 Jun 2. Addict Biol. 2016. PMID: 26037332 Free PMC article.
Treatment with a novel oleic-acid-dihydroxyamphetamine conjugation ameliorates non-alcoholic fatty liver disease in obese Zucker rats.
Decara JM, Pavón FJ, Suárez J, Romero-Cuevas M, Baixeras E, Vázquez M, Rivera P, Gavito AL, Almeida B, Joglar J, de la Torre R, Rodríguez de Fonseca F, Serrano A. Decara JM, et al. Among authors: baixeras e. Dis Model Mech. 2015 Oct 1;8(10):1213-25. doi: 10.1242/dmm.019919. Dis Model Mech. 2015. PMID: 26438694 Free PMC article.
58 results