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Protein phosphatase 2A holoenzymes regulate leucine-rich repeat kinase 2 phosphorylation and accumulation.
Drouyer M, Bolliger MF, Lobbestael E, Van den Haute C, Emanuele M, Lefebvre R, Sibran W, De Wit T, Leghay C, Mutez E, Dzamko N, Halliday GM, Murayama S, Martoriati A, Cailliau K, Bodart JF, Chartier-Harlin MC, Baekelandt V, Nichols RJ, Taymans JM. Drouyer M, et al. Among authors: baekelandt v. Neurobiol Dis. 2021 Sep;157:105426. doi: 10.1016/j.nbd.2021.105426. Epub 2021 Jun 16. Neurobiol Dis. 2021. PMID: 34144124 Free article.
Distribution of PINK1 and LRRK2 in rat and mouse brain.
Taymans JM, Van den Haute C, Baekelandt V. Taymans JM, et al. Among authors: baekelandt v. J Neurochem. 2006 Aug;98(3):951-61. doi: 10.1111/j.1471-4159.2006.03919.x. Epub 2006 Jun 12. J Neurochem. 2006. PMID: 16771836 Free article.
The Parkinson disease-associated leucine-rich repeat kinase 2 (LRRK2) is a dimer that undergoes intramolecular autophosphorylation.
Greggio E, Zambrano I, Kaganovich A, Beilina A, Taymans JM, Daniëls V, Lewis P, Jain S, Ding J, Syed A, Thomas KJ, Baekelandt V, Cookson MR. Greggio E, et al. Among authors: baekelandt v. J Biol Chem. 2008 Jun 13;283(24):16906-14. doi: 10.1074/jbc.M708718200. Epub 2008 Apr 8. J Biol Chem. 2008. PMID: 18397888 Free PMC article.
The Parkinson's disease kinase LRRK2 autophosphorylates its GTPase domain at multiple sites.
Greggio E, Taymans JM, Zhen EY, Ryder J, Vancraenenbroeck R, Beilina A, Sun P, Deng J, Jaffe H, Baekelandt V, Merchant K, Cookson MR. Greggio E, et al. Among authors: baekelandt v. Biochem Biophys Res Commun. 2009 Nov 20;389(3):449-54. doi: 10.1016/j.bbrc.2009.08.163. Epub 2009 Sep 3. Biochem Biophys Res Commun. 2009. PMID: 19733152 Free PMC article.
202 results