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Epigenetic regulation of brain region-specific microglia clearance activity.
Ayata P, Badimon A, Strasburger HJ, Duff MK, Montgomery SE, Loh YE, Ebert A, Pimenova AA, Ramirez BR, Chan AT, Sullivan JM, Purushothaman I, Scarpa JR, Goate AM, Busslinger M, Shen L, Losic B, Schaefer A. Ayata P, et al. Among authors: badimon a. Nat Neurosci. 2018 Aug;21(8):1049-1060. doi: 10.1038/s41593-018-0192-3. Epub 2018 Jul 23. Nat Neurosci. 2018. PMID: 30038282 Free PMC article.
Polycomb repressive complex 2 (PRC2) silences genes responsible for neurodegeneration.
von Schimmelmann M, Feinberg PA, Sullivan JM, Ku SM, Badimon A, Duff MK, Wang Z, Lachmann A, Dewell S, Ma'ayan A, Han MH, Tarakhovsky A, Schaefer A. von Schimmelmann M, et al. Among authors: badimon a. Nat Neurosci. 2016 Oct;19(10):1321-30. doi: 10.1038/nn.4360. Epub 2016 Aug 15. Nat Neurosci. 2016. PMID: 27526204 Free PMC article.
Negative feedback control of neuronal activity by microglia.
Badimon A, Strasburger HJ, Ayata P, Chen X, Nair A, Ikegami A, Hwang P, Chan AT, Graves SM, Uweru JO, Ledderose C, Kutlu MG, Wheeler MA, Kahan A, Ishikawa M, Wang YC, Loh YE, Jiang JX, Surmeier DJ, Robson SC, Junger WG, Sebra R, Calipari ES, Kenny PJ, Eyo UB, Colonna M, Quintana FJ, Wake H, Gradinaru V, Schaefer A. Badimon A, et al. Nature. 2020 Oct;586(7829):417-423. doi: 10.1038/s41586-020-2777-8. Epub 2020 Sep 30. Nature. 2020. PMID: 32999463 Free PMC article.
Sensory lesioning induces microglial synapse elimination via ADAM10 and fractalkine signaling.
Gunner G, Cheadle L, Johnson KM, Ayata P, Badimon A, Mondo E, Nagy MA, Liu L, Bemiller SM, Kim KW, Lira SA, Lamb BT, Tapper AR, Ransohoff RM, Greenberg ME, Schaefer A, Schafer DP. Gunner G, et al. Among authors: badimon a. Nat Neurosci. 2019 Jul;22(7):1075-1088. doi: 10.1038/s41593-019-0419-y. Epub 2019 Jun 17. Nat Neurosci. 2019. PMID: 31209379 Free PMC article.
Autism-like syndrome is induced by pharmacological suppression of BET proteins in young mice.
Sullivan JM, Badimon A, Schaefer U, Ayata P, Gray J, Chung CW, von Schimmelmann M, Zhang F, Garton N, Smithers N, Lewis H, Tarakhovsky A, Prinjha RK, Schaefer A. Sullivan JM, et al. Among authors: badimon a. J Exp Med. 2015 Oct 19;212(11):1771-81. doi: 10.1084/jem.20151271. Epub 2015 Sep 21. J Exp Med. 2015. PMID: 26392221 Free PMC article.
CSF-1 controls cerebellar microglia and is required for motor function and social interaction.
Kana V, Desland FA, Casanova-Acebes M, Ayata P, Badimon A, Nabel E, Yamamuro K, Sneeboer M, Tan IL, Flanigan ME, Rose SA, Chang C, Leader A, Le Bourhis H, Sweet ES, Tung N, Wroblewska A, Lavin Y, See P, Baccarini A, Ginhoux F, Chitu V, Stanley ER, Russo SJ, Yue Z, Brown BD, Joyner AL, De Witte LD, Morishita H, Schaefer A, Merad M. Kana V, et al. Among authors: badimon a. J Exp Med. 2019 Oct 7;216(10):2265-2281. doi: 10.1084/jem.20182037. Epub 2019 Jul 26. J Exp Med. 2019. PMID: 31350310 Free PMC article.
Susceptibility to chronic social stress increases plaque progression, vulnerability and platelet activation.
Giannarelli C, Rodriguez DT, Zafar MU, Christoffel D, Vialou V, Peña C, Badimon A, Hodes GF, Mury P, Rabkin J, Alique M, Villa G, Argmann C, Nestler EJ, Russo SJ, Badimon JJ. Giannarelli C, et al. Among authors: badimon a. Thromb Haemost. 2017 Apr 3;117(4):816-818. doi: 10.1160/TH16-10-0817. Epub 2017 Jan 12. Thromb Haemost. 2017. PMID: 28078352 Free PMC article. No abstract available.
Microglia-astrocyte crosstalk regulates synapse remodeling via Wnt signaling.
Faust TE, Lee YH, O'Connor CD, Boyle MA, Gunner G, Badimon A, Ayata P, Schaefer A, Schafer DP. Faust TE, et al. Among authors: badimon a. bioRxiv [Preprint]. 2024 Feb 9:2024.02.08.579178. doi: 10.1101/2024.02.08.579178. bioRxiv. 2024. PMID: 38370645 Free PMC article. Preprint.
11 results