Search Page
Save citations to file
Email citations
Send citations to clipboard
Add to Collections
Add to My Bibliography
Create a file for external citation management software
Your saved search
Your RSS Feed
Search Results
8 results
Filters applied: . Clear all
Results are displayed in a computed author sort order.
The Results By Year timeline is not available.
Page 1
Multivalent Small-Molecule Pan-RAS Inhibitors.
Cell. 2017 Feb 23;168(5):878-889.e29. doi: 10.1016/j.cell.2017.02.006.
Cell. 2017.
PMID: 28235199
Free PMC article.
Cysteine depletion induces pancreatic tumor ferroptosis in mice.
Badgley MA, Kremer DM, Maurer HC, DelGiorno KE, Lee HJ, Purohit V, Sagalovskiy IR, Ma A, Kapilian J, Firl CEM, Decker AR, Sastra SA, Palermo CF, Andrade LR, Sajjakulnukit P, Zhang L, Tolstyka ZP, Hirschhorn T, Lamb C, Liu T, Gu W, Seeley ES, Stone E, Georgiou G, Manor U, Iuga A, Wahl GM, Stockwell BR, Lyssiotis CA, Olive KP.
Badgley MA, et al.
Science. 2020 Apr 3;368(6486):85-89. doi: 10.1126/science.aaw9872.
Science. 2020.
PMID: 32241947
Free PMC article.
Item in Clipboard
GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis.
Kremer DM, Nelson BS, Lin L, Yarosz EL, Halbrook CJ, Kerk SA, Sajjakulnukit P, Myers A, Thurston G, Hou SW, Carpenter ES, Andren AC, Nwosu ZC, Cusmano N, Wisner S, Mbah NE, Shan M, Das NK, Magnuson B, Little AC, Savani MR, Ramos J, Gao T, Sastra SA, Palermo CF, Badgley MA, Zhang L, Asara JM, McBrayer SK, di Magliano MP, Crawford HC, Shah YM, Olive KP, Lyssiotis CA.
Kremer DM, et al. Among authors: badgley ma.
Nat Commun. 2021 Aug 11;12(1):4860. doi: 10.1038/s41467-021-24859-2.
Nat Commun. 2021.
PMID: 34381026
Free PMC article.
Item in Clipboard
Adaptive stimulation of macropinocytosis overcomes aspartate limitation in cancer cells under hypoxia.
Garcia-Bermudez J, Badgley MA, Prasad S, Baudrier L, Liu Y, La K, Soula M, Williams RT, Yamaguchi N, Hwang RF, Taylor LJ, de Stanchina E, Rostandy B, Alwaseem H, Molina H, Bar-Sagi D, Birsoy K.
Garcia-Bermudez J, et al. Among authors: badgley ma.
Nat Metab. 2022 Jun;4(6):724-738. doi: 10.1038/s42255-022-00583-z. Epub 2022 Jun 20.
Nat Metab. 2022.
PMID: 35726024
Free PMC article.
Item in Clipboard
Exploiting cancer's drinking problem: regulation and therapeutic potential of macropinocytosis.
Puccini J, Badgley MA, Bar-Sagi D.
Puccini J, et al. Among authors: badgley ma.
Trends Cancer. 2022 Jan;8(1):54-64. doi: 10.1016/j.trecan.2021.09.004. Epub 2021 Oct 11.
Trends Cancer. 2022.
PMID: 34649835
Free PMC article.
Review.
Item in Clipboard
Tumor-selective activity of RAS-GTP inhibition in pancreatic cancer.
Wasko UN, Jiang J, Dalton TC, Curiel-Garcia A, Edwards AC, Wang Y, Lee B, Orlen M, Tian S, Stalnecker CA, Drizyte-Miller K, Menard M, Dilly J, Sastra SA, Palermo CF, Hasselluhn MC, Decker-Farrell AR, Chang S, Jiang L, Wei X, Yang YC, Helland C, Courtney H, Gindin Y, Muonio K, Zhao R, Kemp SB, Clendenin C, Sor R, Vostrejs WP, Hibshman PS, Amparo AM, Hennessey C, Rees MG, Ronan MM, Roth JA, Brodbeck J, Tomassoni L, Bakir B, Socci ND, Herring LE, Barker NK, Wang J, Cleary JM, Wolpin BM, Chabot JA, Kluger MD, Manji GA, Tsai KY, Sekulic M, Lagana SM, Califano A, Quintana E, Wang Z, Smith JAM, Holderfield M, Wildes D, Lowe SW, Badgley MA, Aguirre AJ, Vonderheide RH, Stanger BZ, Baslan T, Der CJ, Singh M, Olive KP.
Wasko UN, et al. Among authors: badgley ma.
Nature. 2024 Apr 8. doi: 10.1038/s41586-024-07379-z. Online ahead of print.
Nature. 2024.
PMID: 38588697
Item in Clipboard
Tumor-selective effects of active RAS inhibition in pancreatic ductal adenocarcinoma.
Wasko UN, Jiang J, Curiel-Garcia A, Wang Y, Lee B, Orlen M, Drizyte-Miller K, Menard M, Dilly J, Sastra SA, Palermo CF, Dalton T, Hasselluhn MC, Decker-Farrell AR, Chang S, Jiang L, Wei X, Yang YC, Helland C, Courtney H, Gindin Y, Zhao R, Kemp SB, Clendenin C, Sor R, Vostrejs W, Amparo AA, Hibshman PS, Rees MG, Ronan MM, Roth JA, Bakir B, Badgley MA, Chabot JA, Kluger MD, Manji GA, Quintana E, Wang Z, Smith JAM, Holderfield M, Wildes D, Aguirre AJ, Der CJ, Vonderheide RH, Stanger BZ, Singh M, Olive KP.
Wasko UN, et al. Among authors: badgley ma.
bioRxiv [Preprint]. 2023 Dec 4:2023.12.03.569791. doi: 10.1101/2023.12.03.569791.
bioRxiv. 2023.
PMID: 38105998
Free PMC article.
Preprint.
Item in Clipboard
Ras-dependent activation of BMAL2 regulates hypoxic metabolism in pancreatic cancer.
Maurer HC, Curiel-Garcia A, Holmstrom S, Laise P, Palermo CF, Sastra SA, Andren A, Li Z, LeLarge T, Sagalovskiy I, Ross DR, Rosario V, Lu K, Ferraiuolo E, Spinosa N, Wong W, Shaw K, Chabot JA, Genkinger J, Hibshoosh H, Manji GA, Iuga A, Schmid RM, Badgley MA, Johnson K, Califano A, Lyssiotis C, Olive KP.
Maurer HC, et al. Among authors: badgley ma.
bioRxiv [Preprint]. 2023 Mar 21:2023.03.19.533333. doi: 10.1101/2023.03.19.533333.
bioRxiv. 2023.
PMID: 36993718
Free PMC article.
Preprint.
Item in Clipboard
Cite
Cite