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P-glycoprotein acts as an immunomodulator during neuroinflammation.
Kooij G, Backer R, Koning JJ, Reijerkerk A, van Horssen J, van der Pol SM, Drexhage J, Schinkel A, Dijkstra CD, den Haan JM, Geijtenbeek TB, de Vries HE. Kooij G, et al. Among authors: backer r. PLoS One. 2009 Dec 8;4(12):e8212. doi: 10.1371/journal.pone.0008212. PLoS One. 2009. PMID: 19997559 Free PMC article.
Notch controls the magnitude of T helper cell responses by promoting cellular longevity.
Helbig C, Gentek R, Backer RA, de Souza Y, Derks IA, Eldering E, Wagner K, Jankovic D, Gridley T, Moerland PD, Flavell RA, Amsen D. Helbig C, et al. Among authors: backer ra. Proc Natl Acad Sci U S A. 2012 Jun 5;109(23):9041-6. doi: 10.1073/pnas.1206044109. Epub 2012 May 21. Proc Natl Acad Sci U S A. 2012. PMID: 22615412 Free PMC article.
A central role for Notch in effector CD8(+) T cell differentiation.
Backer RA, Helbig C, Gentek R, Kent A, Laidlaw BJ, Dominguez CX, de Souza YS, van Trierum SE, van Beek R, Rimmelzwaan GF, ten Brinke A, Willemsen AM, van Kampen AH, Kaech SM, Blander JM, van Gisbergen K, Amsen D. Backer RA, et al. Nat Immunol. 2014 Dec;15(12):1143-51. doi: 10.1038/ni.3027. Epub 2014 Oct 26. Nat Immunol. 2014. PMID: 25344724 Free PMC article.
Decisions on the road to memory.
Amsen D, Backer RA, Helbig C. Amsen D, et al. Adv Exp Med Biol. 2013;785:107-20. doi: 10.1007/978-1-4614-6217-0_12. Adv Exp Med Biol. 2013. PMID: 23456843 Review.
98 results