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Hepatitis B Virus Evasion From Cyclic Guanosine Monophosphate-Adenosine Monophosphate Synthase Sensing in Human Hepatocytes.
Verrier ER, Yim SA, Heydmann L, El Saghire H, Bach C, Turon-Lagot V, Mailly L, Durand SC, Lucifora J, Durantel D, Pessaux P, Manel N, Hirsch I, Zeisel MB, Pochet N, Schuster C, Baumert TF. Verrier ER, et al. Among authors: bach c. Hepatology. 2018 Nov;68(5):1695-1709. doi: 10.1002/hep.30054. Epub 2018 Jul 10. Hepatology. 2018. PMID: 29679386 Free PMC article.
A targeted functional RNA interference screen uncovers glypican 5 as an entry factor for hepatitis B and D viruses.
Verrier ER, Colpitts CC, Bach C, Heydmann L, Weiss A, Renaud M, Durand SC, Habersetzer F, Durantel D, Abou-Jaoudé G, López Ledesma MM, Felmlee DJ, Soumillon M, Croonenborghs T, Pochet N, Nassal M, Schuster C, Brino L, Sureau C, Zeisel MB, Baumert TF. Verrier ER, et al. Among authors: bach c. Hepatology. 2016 Jan;63(1):35-48. doi: 10.1002/hep.28013. Epub 2015 Oct 6. Hepatology. 2016. PMID: 26224662
Solute Carrier NTCP Regulates Innate Antiviral Immune Responses Targeting Hepatitis C Virus Infection of Hepatocytes.
Verrier ER, Colpitts CC, Bach C, Heydmann L, Zona L, Xiao F, Thumann C, Crouchet E, Gaudin R, Sureau C, Cosset FL, McKeating JA, Pessaux P, Hoshida Y, Schuster C, Zeisel MB, Baumert TF. Verrier ER, et al. Among authors: bach c. Cell Rep. 2016 Oct 25;17(5):1357-1368. doi: 10.1016/j.celrep.2016.09.084. Cell Rep. 2016. PMID: 27783949 Free PMC article.
Combined small molecule and loss-of-function screen uncovers estrogen receptor alpha and CAD as host factors for HDV infection and antiviral targets.
Verrier ER, Weiss A, Bach C, Heydmann L, Turon-Lagot V, Kopp A, El Saghire H, Crouchet E, Pessaux P, Garcia T, Pale P, Zeisel MB, Sureau C, Schuster C, Brino L, Baumert TF. Verrier ER, et al. Among authors: bach c. Gut. 2020 Jan;69(1):158-167. doi: 10.1136/gutjnl-2018-317065. Epub 2019 Mar 4. Gut. 2020. PMID: 30833451 Free PMC article.
A genome-wide gain-of-function screen identifies CDKN2C as a HBV host factor.
Eller C, Heydmann L, Colpitts CC, El Saghire H, Piccioni F, Jühling F, Majzoub K, Pons C, Bach C, Lucifora J, Lupberger J, Nassal M, Cowley GS, Fujiwara N, Hsieh SY, Hoshida Y, Felli E, Pessaux P, Sureau C, Schuster C, Root DE, Verrier ER, Baumert TF. Eller C, et al. Among authors: bach c. Nat Commun. 2020 Jun 1;11(1):2707. doi: 10.1038/s41467-020-16517-w. Nat Commun. 2020. PMID: 32483149 Free PMC article.
The circadian clock component BMAL1 regulates SARS-CoV-2 entry and replication in lung epithelial cells.
Zhuang X, Tsukuda S, Wrensch F, Wing PAC, Schilling M, Harris JM, Borrmann H, Morgan SB, Cane JL, Mailly L, Thakur N, Conceicao C, Sanghani H, Heydmann L, Bach C, Ashton A, Walsh S, Tan TK, Schimanski L, Huang KA, Schuster C, Watashi K, Hinks TSC, Jagannath A, Vausdevan SR, Bailey D, Baumert TF, McKeating JA. Zhuang X, et al. Among authors: bach c. iScience. 2021 Oct 22;24(10):103144. doi: 10.1016/j.isci.2021.103144. Epub 2021 Sep 16. iScience. 2021. PMID: 34545347 Free PMC article.
A stable hepatitis D virus-producing cell line for host target and drug discovery.
Bach C, Lucifora J, Delphin M, Heydmann L, Heuschkel MJ, Pons C, Goto K, Scheers E, Schuster C, Durantel D, Pauwels F, Baumert TF, Verrier ER. Bach C, et al. Antiviral Res. 2023 Jan;209:105477. doi: 10.1016/j.antiviral.2022.105477. Epub 2022 Nov 26. Antiviral Res. 2023. PMID: 36511319 Free article.
Hepatitis D virus interferes with hepatitis B virus RNA production via interferon-dependent and -independent mechanisms.
Lucifora J, Alfaiate D, Pons C, Michelet M, Ramirez R, Fusil F, Amirache F, Rossi A, Legrand AF, Charles E, Vegna S, Farhat R, Rivoire M, Passot G, Gadot N, Testoni B, Bach C, Baumert TF, Hyrina A, Beran RK, Zoulim F, Boonstra A, Büning H, Verrier ER, Cosset FL, Fletcher SP, Salvetti A, Durantel D. Lucifora J, et al. Among authors: bach c. J Hepatol. 2023 May;78(5):958-970. doi: 10.1016/j.jhep.2023.01.005. Epub 2023 Jan 24. J Hepatol. 2023. PMID: 36702177
JAK1 promotes HDV replication and is a potential target for antiviral therapy.
Heuschkel MJ, Bach C, Meiss-Heydmann L, Gerges E, Felli E, Giannone F, Pessaux P, Schuster C, Lucifora J, Baumert TF, Verrier ER. Heuschkel MJ, et al. Among authors: bach c. J Hepatol. 2024 Feb;80(2):220-231. doi: 10.1016/j.jhep.2023.10.030. Epub 2023 Nov 2. J Hepatol. 2024. PMID: 37925078 Free article.
568 results