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Page 1
Randomized Trial of Benznidazole for Chronic Chagas' Cardiomyopathy.
N Engl J Med. 2015 Oct;373(14):1295-306. doi: 10.1056/NEJMoa1507574. Epub 2015 Sep 1.
N Engl J Med. 2015.
PMID: 26323937
Free article.
Clinical Trial.
Subgroups of the BENEFIT study: risk of developing MS and treatment effect of interferon beta-1b.
Polman C, Kappos L, Freedman MS, Edan G, Hartung HP, Miller DH, Montalbán X, Barkhof F, Selmaj K, Uitdehaag BM, Dahms S, Bauer L, Pohl C, Sandbrink R; BENEFIT investigators.
Polman C, et al.
J Neurol. 2008 Apr;255(4):480-7. doi: 10.1007/s00415-007-0733-2. Epub 2007 Nov 15.
J Neurol. 2008.
PMID: 18004635
Clinical Trial.
Item in Clipboard
Effects of Trypanocidal Treatment on Echocardiographic Parameters in Chagas Cardiomyopathy and Prognostic Value of Wall Motion Score Index: A BENEFIT Trial Echocardiographic Substudy.
Schmidt A, Dias Romano MM, Marin-Neto JA, Rao-Melacini P, Rassi A Jr, Mattos A, Avezum Á Jr, Villena E, Sosa-Estani S, Bonilla R, Yusuf S, Morillo CA, Maciel BC; BENEFIT Investigators.
Schmidt A, et al.
J Am Soc Echocardiogr. 2019 Feb;32(2):286-295.e3. doi: 10.1016/j.echo.2018.09.006. Epub 2018 Nov 9.
J Am Soc Echocardiogr. 2019.
PMID: 30420161
Clinical Trial.
Item in Clipboard
The BENEFIT trial: testing the hypothesis that trypanocidal therapy is beneficial for patients with chronic Chagas heart disease.
Marin-Neto JA, Rassi A Jr, Avezum A Jr, Mattos AC, Rassi A, Morillo CA, Sosa-Estani S, Yusuf S; BENEFIT Investigators.
Marin-Neto JA, et al.
Mem Inst Oswaldo Cruz. 2009 Jul;104 Suppl 1:319-24. doi: 10.1590/s0074-02762009000900042.
Mem Inst Oswaldo Cruz. 2009.
PMID: 19753491
Free article.
Item in Clipboard
Rationale and design of a randomized placebo-controlled trial assessing the effects of etiologic treatment in Chagas' cardiomyopathy: the BENznidazole Evaluation For Interrupting Trypanosomiasis (BENEFIT).
Marin-Neto JA, Rassi A Jr, Morillo CA, Avezum A, Connolly SJ, Sosa-Estani S, Rosas F, Yusuf S; BENEFIT Investigators.
Marin-Neto JA, et al.
Am Heart J. 2008 Jul;156(1):37-43. doi: 10.1016/j.ahj.2008.04.001.
Am Heart J. 2008.
PMID: 18585495
Clinical Trial.
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