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Targeted pharmacological therapy restores β-cell function for diabetes remission.
Sachs S, Bastidas-Ponce A, Tritschler S, Bakhti M, Böttcher A, Sánchez-Garrido MA, Tarquis-Medina M, Kleinert M, Fischer K, Jall S, Harger A, Bader E, Roscioni S, Ussar S, Feuchtinger A, Yesildag B, Neelakandhan A, Jensen CB, Cornu M, Yang B, Finan B, DiMarchi RD, Tschöp MH, Theis FJ, Hofmann SM, Müller TD, Lickert H. Sachs S, et al. Among authors: bottcher a. Nat Metab. 2020 Feb;2(2):192-209. doi: 10.1038/s42255-020-0171-3. Epub 2020 Feb 20. Nat Metab. 2020. PMID: 32694693
Vertical sleeve gastrectomy triggers fast β-cell recovery upon overt diabetes.
Oppenländer L, Palit S, Stemmer K, Greisle T, Sterr M, Salinno C, Bastidas-Ponce A, Feuchtinger A, Böttcher A, Ansarullah, Theis FJ, Lickert H. Oppenländer L, et al. Among authors: bottcher a. Mol Metab. 2021 Dec;54:101330. doi: 10.1016/j.molmet.2021.101330. Epub 2021 Sep 6. Mol Metab. 2021. PMID: 34500108 Free PMC article.
Modelling the endocrine pancreas in health and disease.
Bakhti M, Böttcher A, Lickert H. Bakhti M, et al. Among authors: bottcher a. Nat Rev Endocrinol. 2019 Mar;15(3):155-171. doi: 10.1038/s41574-018-0132-z. Nat Rev Endocrinol. 2019. PMID: 30504925 Review.
Point mutations in the PDX1 transactivation domain impair human β-cell development and function.
Wang X, Sterr M, Ansarullah, Burtscher I, Böttcher A, Beckenbauer J, Siehler J, Meitinger T, Häring HU, Staiger H, Cernilogar FM, Schotta G, Irmler M, Beckers J, Wright CVE, Bakhti M, Lickert H. Wang X, et al. Among authors: bottcher a. Mol Metab. 2019 Jun;24:80-97. doi: 10.1016/j.molmet.2019.03.006. Epub 2019 Mar 20. Mol Metab. 2019. PMID: 30930126 Free PMC article.
Non-canonical Wnt/PCP signalling regulates intestinal stem cell lineage priming towards enteroendocrine and Paneth cell fates.
Böttcher A, Büttner M, Tritschler S, Sterr M, Aliluev A, Oppenländer L, Burtscher I, Sass S, Irmler M, Beckers J, Ziegenhain C, Enard W, Schamberger AC, Verhamme FM, Eickelberg O, Theis FJ, Lickert H. Böttcher A, et al. Nat Cell Biol. 2021 Jan;23(1):23-31. doi: 10.1038/s41556-020-00617-2. Epub 2021 Jan 4. Nat Cell Biol. 2021. PMID: 33398177
CD81 marks immature and dedifferentiated pancreatic β-cells.
Salinno C, Büttner M, Cota P, Tritschler S, Tarquis-Medina M, Bastidas-Ponce A, Scheibner K, Burtscher I, Böttcher A, Theis FJ, Bakhti M, Lickert H. Salinno C, et al. Among authors: bottcher a. Mol Metab. 2021 Jul;49:101188. doi: 10.1016/j.molmet.2021.101188. Epub 2021 Feb 11. Mol Metab. 2021. PMID: 33582383 Free PMC article.
Author Correction: Non-canonical Wnt/PCP signalling regulates intestinal stem cell lineage priming towards enteroendocrine and Paneth cell fates.
Böttcher A, Büttner M, Tritschler S, Sterr M, Aliluev A, Oppenländer L, Burtscher I, Sass S, Irmler M, Beckers J, Ziegenhain C, Enard W, Schamberger AC, Verhamme FM, Eickelberg O, Theis FJ, Lickert H. Böttcher A, et al. Nat Cell Biol. 2021 May;23(5):566-576. doi: 10.1038/s41556-021-00667-0. Nat Cell Biol. 2021. PMID: 33864032 No abstract available.
191 results