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Point mutations in the PDX1 transactivation domain impair human β-cell development and function.
Wang X, Sterr M, Ansarullah, Burtscher I, Böttcher A, Beckenbauer J, Siehler J, Meitinger T, Häring HU, Staiger H, Cernilogar FM, Schotta G, Irmler M, Beckers J, Wright CVE, Bakhti M, Lickert H. Wang X, et al. Among authors: bottcher a. Mol Metab. 2019 Jun;24:80-97. doi: 10.1016/j.molmet.2019.03.006. Epub 2019 Mar 20. Mol Metab. 2019. PMID: 30930126 Free PMC article.
Engineering Skin with Skinny Genes.
Böttcher A, Lickert H, Tschöp M. Böttcher A, et al. Cell Stem Cell. 2017 Aug 3;21(2):153-155. doi: 10.1016/j.stem.2017.07.013. Cell Stem Cell. 2017. PMID: 28777938 Free article.
Modelling the endocrine pancreas in health and disease.
Bakhti M, Böttcher A, Lickert H. Bakhti M, et al. Among authors: bottcher a. Nat Rev Endocrinol. 2019 Mar;15(3):155-171. doi: 10.1038/s41574-018-0132-z. Nat Rev Endocrinol. 2019. PMID: 30504925 Review.
Targeted pharmacological therapy restores β-cell function for diabetes remission.
Sachs S, Bastidas-Ponce A, Tritschler S, Bakhti M, Böttcher A, Sánchez-Garrido MA, Tarquis-Medina M, Kleinert M, Fischer K, Jall S, Harger A, Bader E, Roscioni S, Ussar S, Feuchtinger A, Yesildag B, Neelakandhan A, Jensen CB, Cornu M, Yang B, Finan B, DiMarchi RD, Tschöp MH, Theis FJ, Hofmann SM, Müller TD, Lickert H. Sachs S, et al. Among authors: bottcher a. Nat Metab. 2020 Feb;2(2):192-209. doi: 10.1038/s42255-020-0171-3. Epub 2020 Feb 20. Nat Metab. 2020. PMID: 32694693
Identification and characterization of distinct brown adipocyte subtypes in C57BL/6J mice.
Karlina R, Lutter D, Miok V, Fischer D, Altun I, Schöttl T, Schorpp K, Israel A, Cero C, Johnson JW, Kapser-Fischer I, Böttcher A, Keipert S, Feuchtinger A, Graf E, Strom T, Walch A, Lickert H, Walzthoeni T, Heinig M, Theis FJ, García-Cáceres C, Cypess AM, Ussar S. Karlina R, et al. Among authors: bottcher a. Life Sci Alliance. 2020 Nov 30;4(1):e202000924. doi: 10.26508/lsa.202000924. Print 2021 Jan. Life Sci Alliance. 2020. PMID: 33257475 Free PMC article.
Non-canonical Wnt/PCP signalling regulates intestinal stem cell lineage priming towards enteroendocrine and Paneth cell fates.
Böttcher A, Büttner M, Tritschler S, Sterr M, Aliluev A, Oppenländer L, Burtscher I, Sass S, Irmler M, Beckers J, Ziegenhain C, Enard W, Schamberger AC, Verhamme FM, Eickelberg O, Theis FJ, Lickert H. Böttcher A, et al. Nat Cell Biol. 2021 Jan;23(1):23-31. doi: 10.1038/s41556-020-00617-2. Epub 2021 Jan 4. Nat Cell Biol. 2021. PMID: 33398177
191 results