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The SWI/SNF complex is a mechanoregulated inhibitor of YAP and TAZ.
Chang L, Azzolin L, Di Biagio D, Zanconato F, Battilana G, Lucon Xiccato R, Aragona M, Giulitti S, Panciera T, Gandin A, Sigismondo G, Krijgsveld J, Fassan M, Brusatin G, Cordenonsi M, Piccolo S. Chang L, et al. Among authors: azzolin l. Nature. 2018 Nov;563(7730):265-269. doi: 10.1038/s41586-018-0658-1. Epub 2018 Oct 31. Nature. 2018. PMID: 30401838 Free PMC article.
A TIAM Double Hit to Oppose YAP/TAZ.
Azzolin L, Piccolo S. Azzolin L, et al. Cancer Cell. 2017 May 8;31(5):607-608. doi: 10.1016/j.ccell.2017.04.009. Cancer Cell. 2017. PMID: 28486099 Free PMC article.
Mechanobiology of YAP and TAZ in physiology and disease.
Panciera T, Azzolin L, Cordenonsi M, Piccolo S. Panciera T, et al. Among authors: azzolin l. Nat Rev Mol Cell Biol. 2017 Dec;18(12):758-770. doi: 10.1038/nrm.2017.87. Epub 2017 Sep 27. Nat Rev Mol Cell Biol. 2017. PMID: 28951564 Free PMC article. Review.
De Novo Generation of Somatic Stem Cells by YAP/TAZ.
Panciera T, Azzolin L, Di Biagio D, Totaro A, Cordenonsi M, Piccolo S. Panciera T, et al. Among authors: azzolin l. J Vis Exp. 2018 May 7;(135):57462. doi: 10.3791/57462. J Vis Exp. 2018. PMID: 29782008 Free PMC article.
Transcriptional addiction in cancer cells is mediated by YAP/TAZ through BRD4.
Zanconato F, Battilana G, Forcato M, Filippi L, Azzolin L, Manfrin A, Quaranta E, Di Biagio D, Sigismondo G, Guzzardo V, Lejeune P, Haendler B, Krijgsveld J, Fassan M, Bicciato S, Cordenonsi M, Piccolo S. Zanconato F, et al. Among authors: azzolin l. Nat Med. 2018 Oct;24(10):1599-1610. doi: 10.1038/s41591-018-0158-8. Epub 2018 Sep 17. Nat Med. 2018. PMID: 30224758 Free PMC article.
Cell phenotypic plasticity requires autophagic flux driven by YAP/TAZ mechanotransduction.
Totaro A, Zhuang Q, Panciera T, Battilana G, Azzolin L, Brumana G, Gandin A, Brusatin G, Cordenonsi M, Piccolo S. Totaro A, et al. Among authors: azzolin l. Proc Natl Acad Sci U S A. 2019 Sep 3;116(36):17848-17857. doi: 10.1073/pnas.1908228116. Epub 2019 Aug 15. Proc Natl Acad Sci U S A. 2019. PMID: 31416916 Free PMC article.
32 results