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2021 9
2022 12
2023 11
2024 1

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28 results

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Page 1
Multi-target rational design and synthesis of novel diphenyl-tethered pyrazolopyrimidines targeting EGFR and topoisomerase II with potential DNA intercalation and apoptosis induction.
Gaber AA, Abo Elmaaty A, Sharaky M, Mosa AA, Yahya Abdullah Alzahrani A, Shaaban S, Eldehna WM, Al-Karmalawy AA. Gaber AA, et al. Among authors: abo elmaaty a. Bioorg Chem. 2024 Apr;145:107223. doi: 10.1016/j.bioorg.2024.107223. Epub 2024 Feb 17. Bioorg Chem. 2024. PMID: 38387399
Partnering essential oils with antibiotics: proven therapies against bovine Staphylococcus aureus mastitis.
Abd El-Hamid MI, El-Tarabili RM, Bahnass MM, Alshahrani MA, Saif A, Alwutayd KM, Safhi FA, Mansour AT, Alblwi NAN, Ghoneim MM, Elmaaty AA, Al-Harthi HF, Bendary MM. Abd El-Hamid MI, et al. Among authors: elmaaty aa. Front Cell Infect Microbiol. 2023 Sep 15;13:1265027. doi: 10.3389/fcimb.2023.1265027. eCollection 2023. Front Cell Infect Microbiol. 2023. PMID: 37790910 Free PMC article.
Design and Synthesis of Novel 5-((3-(Trifluoromethyl)piperidin-1-yl)sulfonyl)indoline-2,3-dione Derivatives as Promising Antiviral Agents: In Vitro, In Silico, and Structure-Activity Relationship Studies.
Ezz Eldin RR, Saleh MA, Alwarsh SA, Rushdi A, Althoqapy AA, El Saeed HS, Abo Elmaaty A. Ezz Eldin RR, et al. Among authors: abo elmaaty a. Pharmaceuticals (Basel). 2023 Sep 4;16(9):1247. doi: 10.3390/ph16091247. Pharmaceuticals (Basel). 2023. PMID: 37765055 Free PMC article.
Investigating the promising SARS-CoV-2 main protease inhibitory activity of secoiridoids isolated from Jasminum humile; in silico and in Vitro assessments with structure-activity relationship.
Al-Karmalawy AA, Alnajjar R, Elmaaty AA, Binjubair FA, Al-Rashood ST, Mansour BS, Elkamhawy A, Eldehna WM, Mansour KA. Al-Karmalawy AA, et al. Among authors: elmaaty aa. J Biomol Struct Dyn. 2023 Jul 28:1-13. doi: 10.1080/07391102.2023.2240419. Online ahead of print. J Biomol Struct Dyn. 2023. PMID: 37505066
Novel topoisomerase II/EGFR dual inhibitors: design, synthesis and docking studies of naphtho[2',3':4,5]thiazolo[3,2-a]pyrimidine hybrids as potential anticancer agents with apoptosis inducing activity.
Mourad MAE, Abo Elmaaty A, Zaki I, Mourad AAE, Hofni A, Khodir AE, Aboubakr EM, Elkamhawy A, Roh EJ, Al-Karmalawy AA. Mourad MAE, et al. Among authors: abo elmaaty a. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2205043. doi: 10.1080/14756366.2023.2205043. J Enzyme Inhib Med Chem. 2023. PMID: 37165800 Free PMC article.
Experimental design of D-α-tocopherol polyethylene glycol 1000 succinate stabilized bile salt based Nano-vesicles for improved cytotoxicity and bioavailability of colchicine binding site inhibitor Candidates: In Vitro, in silico, and pharmacokinetic studies.
Abo Elmaaty A, Al-Karmalawy AA, Nafie MS, Shamaa MM, Zaki I, Alnajjar R, Zakaria MY. Abo Elmaaty A, et al. Int J Pharm. 2023 Jun 10;640:122980. doi: 10.1016/j.ijpharm.2023.122980. Epub 2023 Apr 26. Int J Pharm. 2023. PMID: 37116601
Tamarindus indica Extract as a Promising Antimicrobial and Antivirulence Therapy.
Ghaly MF, Albalawi MA, Bendary MM, Shahin A, Shaheen MA, Abu Eleneen AF, Ghoneim MM, Elmaaty AA, Elrefai MFM, Zaitone SA, Abousaty AI. Ghaly MF, et al. Among authors: elmaaty aa. Antibiotics (Basel). 2023 Feb 24;12(3):464. doi: 10.3390/antibiotics12030464. Antibiotics (Basel). 2023. PMID: 36978330 Free PMC article.
Investigating the potential anticancer activities of antibiotics as topoisomerase II inhibitors and DNA intercalators: in vitro, molecular docking, molecular dynamics, and SAR studies.
Farouk F, Elmaaty AA, Elkamhawy A, Tawfik HO, Alnajjar R, Abourehab MAS, Saleh MA, Eldehna WM, Al-Karmalawy AA. Farouk F, et al. Among authors: elmaaty aa. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2171029. doi: 10.1080/14756366.2023.2171029. J Enzyme Inhib Med Chem. 2023. PMID: 36701269 Free PMC article.
28 results