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First clinical-grade porcine kidney xenotransplant using a human decedent model.
Porrett PM, Orandi BJ, Kumar V, Houp J, Anderson D, Cozette Killian A, Hauptfeld-Dolejsek V, Martin DE, Macedon S, Budd N, Stegner KL, Dandro A, Kokkinaki M, Kuravi KV, Reed RD, Fatima H, Killian JT Jr, Baker G, Perry J, Wright ED, Cheung MD, Erman EN, Kraebber K, Gamblin T, Guy L, George JF, Ayares D, Locke JE. Porrett PM, et al. Among authors: ayares d. Am J Transplant. 2022 Apr;22(4):1037-1053. doi: 10.1111/ajt.16930. Epub 2022 Jan 20. Am J Transplant. 2022. PMID: 35049121 Free article.
Production and characterization of transgenic pigs expressing porcine CTLA4-Ig.
Phelps CJ, Ball SF, Vaught TD, Vance AM, Mendicino M, Monahan JA, Walters AH, Wells KD, Dandro AS, Ramsoondar JJ, Cooper DK, Ayares DL. Phelps CJ, et al. Among authors: ayares dl. Xenotransplantation. 2009 Nov-Dec;16(6):477-85. doi: 10.1111/j.1399-3089.2009.00533.x. Xenotransplantation. 2009. PMID: 20042047
Targeted disruption of the porcine immunoglobulin kappa light chain locus.
Ramsoondar J, Mendicino M, Phelps C, Vaught T, Ball S, Monahan J, Chen S, Dandro A, Boone J, Jobst P, Vance A, Wertz N, Polejaeva I, Butler J, Dai Y, Ayares D, Wells K. Ramsoondar J, et al. Among authors: ayares d. Transgenic Res. 2011 Jun;20(3):643-53. doi: 10.1007/s11248-010-9445-y. Epub 2010 Sep 26. Transgenic Res. 2011. PMID: 20872247
New concepts of immune modulation in xenotransplantation.
Satyananda V, Hara H, Ezzelarab MB, Phelps C, Ayares D, Cooper DK. Satyananda V, et al. Among authors: ayares d. Transplantation. 2013 Dec 15;96(11):937-45. doi: 10.1097/TP.0b013e31829bbcb2. Transplantation. 2013. PMID: 23851935 Free PMC article. Review.
Regulatory sequences of the porcine THBD gene facilitate endothelial-specific expression of bioactive human thrombomodulin in single- and multitransgenic pigs.
Wuensch A, Baehr A, Bongoni AK, Kemter E, Blutke A, Baars W, Haertle S, Zakhartchenko V, Kurome M, Kessler B, Faber C, Abicht JM, Reichart B, Wanke R, Schwinzer R, Nagashima H, Rieben R, Ayares D, Wolf E, Klymiuk N. Wuensch A, et al. Among authors: ayares d. Transplantation. 2014 Jan 27;97(2):138-47. doi: 10.1097/TP.0b013e3182a95cbc. Transplantation. 2014. PMID: 24150517 Free article.
Transgenic Expression of Human CD46 on Porcine Endothelium: Effect on Coagulation and Fibrinolytic Cascades During Ex Vivo Human-to-Pig Limb Xenoperfusions.
Bongoni AK, Kiermeir D, Schnider J, Jenni H, Garimella P, Bähr A, Klymiuk N, Wolf E, Ayares D, Voegelin E, Constantinescu MA, Seebach JD, Rieben R. Bongoni AK, et al. Among authors: ayares d. Transplantation. 2015 Oct;99(10):2061-9. doi: 10.1097/TP.0000000000000746. Transplantation. 2015. PMID: 25965410
Platelet sequestration and activation during GalTKO.hCD46 pig lung perfusion by human blood is primarily mediated by GPIb, GPIIb/IIIa, and von Willebrand Factor.
Burdorf L, Riner A, Rybak E, Salles II, De Meyer SF, Shah A, Quinn KJ, Harris D, Zhang T, Parsell D, Ali F, Schwartz E, Kang E, Cheng X, Sievert E, Zhao Y, Braileanu G, Phelps CJ, Ayares DL, Deckmyn H, Pierson RN 3rd, Azimzadeh AM, Dandro A, Karavi K. Burdorf L, et al. Among authors: ayares dl. Xenotransplantation. 2016 May;23(3):222-236. doi: 10.1111/xen.12236. Epub 2016 May 18. Xenotransplantation. 2016. PMID: 27188532 Free PMC article.
219 results