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A stromal Integrated Stress Response activates perivascular cancer-associated fibroblasts to drive angiogenesis and tumour progression.
Verginadis II, Avgousti H, Monslow J, Skoufos G, Chinga F, Kim K, Leli NM, Karagounis IV, Bell BI, Velalopoulou A, Salinas CS, Wu VS, Li Y, Ye J, Scott DA, Osterman AL, Sengupta A, Weljie A, Huang M, Zhang D, Fan Y, Radaelli E, Tobias JW, Rambow F, Karras P, Marine JC, Xu X, Hatzigeorgiou AG, Ryeom S, Diehl JA, Fuchs SY, Puré E, Koumenis C. Verginadis II, et al. Among authors: avgousti h. Nat Cell Biol. 2022 Jun;24(6):940-953. doi: 10.1038/s41556-022-00918-8. Epub 2022 Jun 2. Nat Cell Biol. 2022. PMID: 35654839 Free PMC article.
A Novel Mouse Model of Radiation-Induced Cardiac Injury Reveals Biological and Radiological Biomarkers of Cardiac Dysfunction with Potential Clinical Relevance.
Dreyfuss AD, Goia D, Shoniyozov K, Shewale SV, Velalopoulou A, Mazzoni S, Avgousti H, Metzler SD, Bravo PE, Feigenberg SJ, Ky B, Verginadis II, Koumenis C. Dreyfuss AD, et al. Among authors: avgousti h. Clin Cancer Res. 2021 Apr 15;27(8):2266-2276. doi: 10.1158/1078-0432.CCR-20-3882. Epub 2021 Feb 4. Clin Cancer Res. 2021. PMID: 33542079 Free PMC article.
Single-cell profiling reveals inflammatory polarization of human carotid versus femoral plaque leukocytes.
Slysz J, Sinha A, DeBerge M, Singh S, Avgousti H, Lee I, Glinton K, Nagasaka R, Dalal P, Alexandria S, Wai CM, Tellez R, Vescovo M, Sunderraj A, Wang X, Schipma M, Sisk R, Gulati R, Vallejo J, Saigusa R, Lloyd-Jones DM, Lomasney J, Weinberg S, Ho K, Ley K, Giannarelli C, Thorp EB, Feinstein MJ. Slysz J, et al. Among authors: avgousti h. JCI Insight. 2023 Sep 8;8(17):e171359. doi: 10.1172/jci.insight.171359. JCI Insight. 2023. PMID: 37471165 Free PMC article.