Avdeef A - Search Results

1

Perspectives in solubility measurement and interpretation.

Bergström CAS, Avdeef A. Bergström CAS, et al. Among authors: avdeef a. ADMET DMPK. 2019 Apr 5;7(2):88-105. doi: 10.5599/admet.686. eCollection 2019. ADMET DMPK. 2019. PMID: 35350542 Free PMC article. Review.

2

Absorption classification of oral drugs based on molecular surface properties.

Bergström CA, Strafford M, Lazorova L, Avdeef A, Luthman K, Artursson P. Bergström CA, et al. Among authors: avdeef a. J Med Chem. 2003 Feb 13;46(4):558-70. doi: 10.1021/jm020986i. J Med Chem. 2003. PMID: 12570377

3

Dissolution rate and apparent solubility of poorly soluble drugs in biorelevant dissolution media.

Fagerberg JH, Tsinman O, Sun N, Tsinman K, Avdeef A, Bergström CA. Fagerberg JH, et al. Among authors: avdeef a. Mol Pharm. 2010 Oct 4;7(5):1419-30. doi: 10.1021/mp100049m. Epub 2010 Jun 24. Mol Pharm. 2010. PMID: 20507160

4

Prediction of aqueous intrinsic solubility of druglike molecules using Random Forest regression trained with Wiki-pS0 database.

Avdeef A. Avdeef A. ADMET DMPK. 2020 Mar 4;8(1):29-77. doi: 10.5599/admet.766. eCollection 2020. ADMET DMPK. 2020. PMID: 35299775 Free PMC article.

5

Do you know your r²?

Avdeef A. Avdeef A. ADMET DMPK. 2020 Aug 30;9(1):69-74. doi: 10.5599/admet.888. eCollection 2021. ADMET DMPK. 2020. PMID: 35299878 Free PMC article.

6

Can small drugs predict the intrinsic aqueous solubility of 'beyond Rule of 5' big drugs?

Avdeef A, Kansy M. Avdeef A, et al. ADMET DMPK. 2020 Apr 25;8(3):180-206. doi: 10.5599/admet.794. eCollection 2020. ADMET DMPK. 2020. PMID: 35300304 Free PMC article.

7

Multi-lab intrinsic solubility measurement reproducibility in CheqSol and shake-flask methods.

Avdeef A. Avdeef A. ADMET DMPK. 2019 Jun 5;7(3):210-219. doi: 10.5599/admet.698. eCollection 2019. ADMET DMPK. 2019. PMID: 35350660 Free PMC article.

8

Thickness of the aqueous boundary layer in stirred microtitre plate permeability assays (PAMPA and Caco-2), based on the Levich equation.

Avdeef A. Avdeef A. ADMET DMPK. 2022 Dec 6;10(4):249-252. doi: 10.5599/admet.1568. eCollection 2022. ADMET DMPK. 2022. PMID: 36578562 Free PMC article. No abstract available.

9

Cocrystal solubility product analysis - Dual concentration-pH mass action model not dependent on explicit solubility equations.

Avdeef A. Avdeef A. Eur J Pharm Sci. 2017 Dec 15;110:2-18. doi: 10.1016/j.ejps.2017.03.049. Epub 2017 Apr 6. Eur J Pharm Sci. 2017. PMID: 28392495

10

Equilibrium solubility measurement of compounds with low dissolution rate by Higuchi's Facilitated Dissolution Method. A validation study.

Takács-Novák K, Urac M, Horváth P, Völgyi G, Anderson BD, Avdeef A. Takács-Novák K, et al. Among authors: avdeef a. Eur J Pharm Sci. 2017 Aug 30;106:133-141. doi: 10.1016/j.ejps.2017.05.064. Epub 2017 May 31. Eur J Pharm Sci. 2017. PMID: 28577995

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