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Genetic variation influencing DNA methylation provides insights into molecular mechanisms regulating genomic function.
Hawe JS, Wilson R, Schmid KT, Zhou L, Lakshmanan LN, Lehne BC, Kühnel B, Scott WR, Wielscher M, Yew YW, Baumbach C, Lee DP, Marouli E, Bernard M, Pfeiffer L, Matías-García PR, Autio MI, Bourgeois S, Herder C, Karhunen V, Meitinger T, Prokisch H, Rathmann W, Roden M, Sebert S, Shin J, Strauch K, Zhang W, Tan WLW, Hauck SM, Merl-Pham J, Grallert H, Barbosa EGV; MuTHER Consortium; Illig T, Peters A, Paus T, Pausova Z, Deloukas P, Foo RSY, Jarvelin MR, Kooner JS, Loh M, Heinig M, Gieger C, Waldenberger M, Chambers JC. Hawe JS, et al. Among authors: autio mi. Nat Genet. 2022 Jan;54(1):18-29. doi: 10.1038/s41588-021-00969-x. Epub 2022 Jan 3. Nat Genet. 2022. PMID: 34980917
Epigenomes of Human Hearts Reveal New Genetic Variants Relevant for Cardiac Disease and Phenotype.
Tan WLW, Anene-Nzelu CG, Wong E, Lee CJM, Tan HS, Tang SJ, Perrin A, Wu KX, Zheng W, Ashburn RJ, Pan B, Lee MY, Autio MI, Morley MP, Tam WL, Cheung C, Margulies KB, Chen L, Cappola TP, Loh M, Chambers J, Prabhakar S, Foo RSY; CHARGE-Heart Failure Working Group, CHARGE-EchoGen Consortium. Tan WLW, et al. Among authors: autio mi. Circ Res. 2020 Aug 28;127(6):761-777. doi: 10.1161/CIRCRESAHA.120.317254. Epub 2020 Jun 12. Circ Res. 2020. PMID: 32529949 Free PMC article.
Assigning Distal Genomic Enhancers to Cardiac Disease-Causing Genes.
Anene-Nzelu CG, Tan WLW, Lee CJM, Wenhao Z, Perrin A, Dashi A, Tiang Z, Autio MI, Lim B, Wong E, Tan HS, Pan B, Morley MP, Margulies KB, Cappola TP, Foo RS. Anene-Nzelu CG, et al. Among authors: autio mi. Circulation. 2020 Sep;142(9):910-912. doi: 10.1161/CIRCULATIONAHA.120.046040. Epub 2020 Aug 31. Circulation. 2020. PMID: 32866060 Free PMC article. No abstract available.
Variation in CFHR3 determines susceptibility to meningococcal disease by controlling factor H concentrations.
Kumar V, Pouw RB, Autio MI, Sagmeister MG, Phua ZY, Borghini L, Wright VJ, Hoggart C, Pan B, Tan AKY, Binder A, Brouwer MC, Pinnock E, De Groot R, Hazelzet J, Emonts M, Van Der Flier M, Reiter K, Nöthen MM, Hoffmann P; EUCLIDS consortium; Schlapbach LJ, Bellos E, Anderson S, Secka F, Martinón-Torres F, Salas A, Fink C, Carrol ED, Pollard AJ, Coin LJ, Zenz W, Wouters D, Ang LT, Hibberd ML, Levin M, Kuijpers TW, Davila S. Kumar V, et al. Among authors: autio mi. Am J Hum Genet. 2022 Sep 1;109(9):1680-1691. doi: 10.1016/j.ajhg.2022.08.001. Epub 2022 Aug 24. Am J Hum Genet. 2022. PMID: 36007525 Free PMC article.
Trans-interaction of risk loci 6p24.1 and 10q11.21 is associated with endothelial damage in coronary artery disease.
Tay KY, Wu KX, Chioh FWJ, Autio MI, Pek NMQ, Narmada BC, Tan SH, Low AF, Lian MM, Chew EGY, Lau HH, Kao SL, Teo AKK, Foo JN, Foo RSY, Heng CK, Chan MYY, Cheung C. Tay KY, et al. Among authors: autio mi. Atherosclerosis. 2022 Dec;362:11-22. doi: 10.1016/j.atherosclerosis.2022.10.012. Epub 2022 Oct 22. Atherosclerosis. 2022. PMID: 36435092 Free article.
A Roadmap for Human Liver Differentiation from Pluripotent Stem Cells.
Ang LT, Tan AKY, Autio MI, Goh SH, Choo SH, Lee KL, Tan J, Pan B, Lee JJH, Lum JJ, Lim CYY, Yeo IKX, Wong CJY, Liu M, Oh JLL, Chia CPL, Loh CH, Chen A, Chen Q, Weissman IL, Loh KM, Lim B. Ang LT, et al. Among authors: autio mi. Cell Rep. 2018 Feb 20;22(8):2190-2205. doi: 10.1016/j.celrep.2018.01.087. Cell Rep. 2018. PMID: 29466743 Free PMC article.
17 results