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Characterization and engineering of a plastic-degrading aromatic polyesterase.
Austin HP, Allen MD, Donohoe BS, Rorrer NA, Kearns FL, Silveira RL, Pollard BC, Dominick G, Duman R, El Omari K, Mykhaylyk V, Wagner A, Michener WE, Amore A, Skaf MS, Crowley MF, Thorne AW, Johnson CW, Woodcock HL, McGeehan JE, Beckham GT. Austin HP, et al. Proc Natl Acad Sci U S A. 2018 May 8;115(19):E4350-E4357. doi: 10.1073/pnas.1718804115. Epub 2018 Apr 17. Proc Natl Acad Sci U S A. 2018. PMID: 29666242 Free PMC article.
Characterization and engineering of a two-enzyme system for plastics depolymerization.
Knott BC, Erickson E, Allen MD, Gado JE, Graham R, Kearns FL, Pardo I, Topuzlu E, Anderson JJ, Austin HP, Dominick G, Johnson CW, Rorrer NA, Szostkiewicz CJ, Copié V, Payne CM, Woodcock HL, Donohoe BS, Beckham GT, McGeehan JE. Knott BC, et al. Among authors: austin hp. Proc Natl Acad Sci U S A. 2020 Oct 13;117(41):25476-25485. doi: 10.1073/pnas.2006753117. Epub 2020 Sep 28. Proc Natl Acad Sci U S A. 2020. PMID: 32989159 Free PMC article.
Concentration-Dependent Inhibition of Mesophilic PETases on Poly(ethylene terephthalate) Can Be Eliminated by Enzyme Engineering.
Avilan L, Lichtenstein BR, König G, Zahn M, Allen MD, Oliveira L, Clark M, Bemmer V, Graham R, Austin HP, Dominick G, Johnson CW, Beckham GT, McGeehan JE, Pickford AR. Avilan L, et al. Among authors: austin hp. ChemSusChem. 2023 Apr 21;16(8):e202202277. doi: 10.1002/cssc.202202277. Epub 2023 Mar 23. ChemSusChem. 2023. PMID: 36811288
Mechanism-Based Design of Efficient PET Hydrolases.
Wei R, von Haugwitz G, Pfaff L, Mican J, Badenhorst CPS, Liu W, Weber G, Austin HP, Bednar D, Damborsky J, Bornscheuer UT. Wei R, et al. Among authors: austin hp. ACS Catal. 2022 Mar 18;12(6):3382-3396. doi: 10.1021/acscatal.1c05856. Epub 2022 Feb 28. ACS Catal. 2022. PMID: 35368328 Free PMC article. Review.