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Rational Design of Bisubstrate-Type Analogues as Inhibitors of DNA Methyltransferases in Cancer Cells.
Halby L, Menon Y, Rilova E, Pechalrieu D, Masson V, Faux C, Bouhlel MA, David-Cordonnier MH, Novosad N, Aussagues Y, Samson A, Lacroix L, Ausseil F, Fleury L, Guianvarc'h D, Ferroud C, Arimondo PB. Halby L, et al. Among authors: aussagues y. J Med Chem. 2017 Jun 8;60(11):4665-4679. doi: 10.1021/acs.jmedchem.7b00176. Epub 2017 May 23. J Med Chem. 2017. PMID: 28463515
Semisynthetic neoboutomellerone derivatives as ubiquitin-proteasome pathway inhibitors.
Beck J, Guminski Y, Long C, Marcourt L, Derguini F, Plisson F, Grondin A, Vandenberghe I, Vispé S, Brel V, Aussagues Y, Ausseil F, Arimondo PB, Massiot G, Sautel F, Cantagrel F. Beck J, et al. Among authors: aussagues y. Bioorg Med Chem. 2012 Jan 15;20(2):819-31. doi: 10.1016/j.bmc.2011.11.066. Epub 2011 Dec 8. Bioorg Med Chem. 2012. PMID: 22206869
Design, synthesis and biological evaluation of 4-amino-N- (4-aminophenyl)benzamide analogues of quinoline-based SGI-1027 as inhibitors of DNA methylation.
Rilova E, Erdmann A, Gros C, Masson V, Aussagues Y, Poughon-Cassabois V, Rajavelu A, Jeltsch A, Menon Y, Novosad N, Gregoire JM, Vispé S, Schambel P, Ausseil F, Sautel F, Arimondo PB, Cantagrel F. Rilova E, et al. Among authors: aussagues y. ChemMedChem. 2014 Mar;9(3):590-601. doi: 10.1002/cmdc.201300420. ChemMedChem. 2014. PMID: 24678024 Free PMC article.
Dichapetalins from Dichapetalum species and their cytotoxic properties.
Long C, Aussagues Y, Molinier N, Marcourt L, Vendier L, Samson A, Poughon V, Chalo Mutiso PB, Ausseil F, Sautel F, Arimondo PB, Massiot G. Long C, et al. Among authors: aussagues y. Phytochemistry. 2013 Oct;94:184-91. doi: 10.1016/j.phytochem.2013.03.023. Epub 2013 Apr 22. Phytochemistry. 2013. PMID: 23618620
Anticancer activity of koningic acid and semisynthetic derivatives.
Rahier NJ, Molinier N, Long C, Deshmukh SK, Kate AS, Ranadive P, Verekar SA, Jiotode M, Lavhale RR, Tokdar P, Balakrishnan A, Meignan S, Robichon C, Gomes B, Aussagues Y, Samson A, Sautel F, Bailly C. Rahier NJ, et al. Among authors: aussagues y. Bioorg Med Chem. 2015 Jul 1;23(13):3712-21. doi: 10.1016/j.bmc.2015.04.004. Epub 2015 Apr 9. Bioorg Med Chem. 2015. PMID: 25937235
Proteasome inhibitors from Neoboutonia melleri.
Long C, Beck J, Cantagrel F, Marcourt L, Vendier L, David B, Plisson F, Derguini F, Vandenberghe I, Aussagues Y, Ausseil F, Lavaud C, Sautel F, Massiot G. Long C, et al. Among authors: aussagues y. J Nat Prod. 2012 Jan 27;75(1):34-47. doi: 10.1021/np200441h. Epub 2011 Dec 14. J Nat Prod. 2012. PMID: 22168134
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